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Mitochondrial control of microglial phagocytosis by the translocator protein and hexokinase 2 in Alzheimer's disease.
Fairley LH, Lai KO, Wong JH, Chong WJ, Vincent AS, D'Agostino G, Wu X, Naik RR, Jayaraman A, Langley SR, Ruedl C, Barron AM. Fairley LH, et al. Among authors: langley sr. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2209177120. doi: 10.1073/pnas.2209177120. Epub 2023 Feb 14. Proc Natl Acad Sci U S A. 2023. PMID: 36787364 Free PMC article.
The habenula clock influences response to a stressor.
Basnakova A, Cheng RK, Chia JSM, D'Agostino G, Suryadi, Tan GJH, Langley SR, Jesuthasan S. Basnakova A, et al. Among authors: langley sr. Neurobiol Stress. 2021 Sep 23;15:100403. doi: 10.1016/j.ynstr.2021.100403. eCollection 2021 Nov. Neurobiol Stress. 2021. PMID: 34632007 Free PMC article.
A high-resolution map of human RNA translation.
Chothani SP, Adami E, Widjaja AA, Langley SR, Viswanathan S, Pua CJ, Zhihao NT, Harmston N, D'Agostino G, Whiffin N, Mao W, Ouyang JF, Lim WW, Lim S, Lee CQE, Grubman A, Chen J, Kovalik JP, Tryggvason K, Polo JM, Ho L, Cook SA, Rackham OJL, Schafer S. Chothani SP, et al. Among authors: langley sr. Mol Cell. 2022 Aug 4;82(15):2885-2899.e8. doi: 10.1016/j.molcel.2022.06.023. Epub 2022 Jul 15. Mol Cell. 2022. PMID: 35841888 Free article.
Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease.
Ferrari Bardile C, Garcia-Miralles M, Caron NS, Rayan NA, Langley SR, Harmston N, Rondelli AM, Teo RTY, Waltl S, Anderson LM, Bae HG, Jung S, Williams A, Prabhakar S, Petretto E, Hayden MR, Pouladi MA. Ferrari Bardile C, et al. Among authors: langley sr. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9622-9627. doi: 10.1073/pnas.1818042116. Epub 2019 Apr 23. Proc Natl Acad Sci U S A. 2019. PMID: 31015293 Free PMC article.
Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins.
Chothani S, Schäfer S, Adami E, Viswanathan S, Widjaja AA, Langley SR, Tan J, Wang M, Quaife NM, Jian Pua C, D'Agostino G, Guna Shekeran S, George BL, Lim S, Yiqun Cao E, van Heesch S, Witte F, Felkin LE, Christodoulou EG, Dong J, Blachut S, Patone G, Barton PJR, Hubner N, Cook SA, Rackham OJL. Chothani S, et al. Among authors: langley sr. Circulation. 2019 Sep 10;140(11):937-951. doi: 10.1161/CIRCULATIONAHA.119.039596. Epub 2019 Jul 9. Circulation. 2019. PMID: 31284728 Free PMC article.
Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult.
Ziaei A, Garcia-Miralles M, Radulescu CI, Sidik H, Silvin A, Bae HG, Bonnard C, Yusof NABM, Ferrari Bardile C, Tan LJ, Ng AYJ, Tohari S, Dehghani L, Henry L, Yeo XY, Lee S, Venkatesh B, Langley SR, Shaygannejad V, Reversade B, Jung S, Ginhoux F, Pouladi MA. Ziaei A, et al. Among authors: langley sr. Brain Pathol. 2022 Sep;32(5):e13064. doi: 10.1111/bpa.13064. Epub 2022 Mar 13. Brain Pathol. 2022. PMID: 35285112 Free PMC article.
Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects.
Ooi J, Langley SR, Xu X, Utami KH, Sim B, Huang Y, Harmston NP, Tay YL, Ziaei A, Zeng R, Low D, Aminkeng F, Sobota RM, Ginhoux F, Petretto E, Pouladi MA. Ooi J, et al. Among authors: langley sr. Cell Rep. 2019 Feb 26;26(9):2494-2508.e7. doi: 10.1016/j.celrep.2019.02.008. Cell Rep. 2019. PMID: 30811996 Free article.
Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis.
Bao X, Li Q, Chen J, Chen D, Ye C, Dai X, Wang Y, Li X, Rong X, Cheng F, Jiang M, Zhu Z, Ding Y, Sun R, Liu C, Huang L, Jin Y, Li B, Lu J, Wu W, Guo Y, Fu W, Langley SR, Tano V, Fang W, Guo T, Sheng J, Zhao P, Ruan J. Bao X, et al. Among authors: langley sr. Cancer Immunol Res. 2022 Jul 1;10(7):811-828. doi: 10.1158/2326-6066.CIR-21-1101. Cancer Immunol Res. 2022. PMID: 35604302
Ethnicity-Specific Skeletal Muscle Transcriptional Signatures and Their Relevance to Insulin Resistance in Singapore.
Tan ALM, Langley SR, Tan CF, Chai JF, Khoo CM, Leow MK, Khoo EYH, Moreno-Moral A, Pravenec M, Rotival M, Sadananthan SA, Velan SS, Venkataraman K, Chong YS, Lee YS, Sim X, Stunkel W, Liu MH, Tai ES, Petretto E. Tan ALM, et al. Among authors: langley sr. J Clin Endocrinol Metab. 2019 Feb 1;104(2):465-486. doi: 10.1210/jc.2018-00309. J Clin Endocrinol Metab. 2019. PMID: 30137523
51 results