Ong ST - Search Results

1

A single-cell atlas identifies pretreatment features of primary imatinib resistance in chronic myeloid leukemia.

Krishnan V, Schmidt F, Nawaz Z, Venkatesh PN, Lee KL, Ren X, Chan ZE, Yu M, Makheja M, Rayan NA, Lim MGL, Cheung AMS, Bari S, Chng WJ, Than H, Ouyang J, Rackham O, Tan TZ, Hwang WYK, Chuah C, Prabhakar S, Ong ST. Krishnan V, et al. Among authors: ong st. Blood. 2023 Jun 1;141(22):2738-2755. doi: 10.1182/blood.2022017295. Blood. 2023. PMID: 36857629

2

Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition.

Ng KP, Manjeri A, Lee KL, Huang W, Tan SY, Chuah CT, Poellinger L, Ong ST. Ng KP, et al. Among authors: ong st. Blood. 2014 May 22;123(21):3316-26. doi: 10.1182/blood-2013-07-511907. Epub 2014 Apr 4. Blood. 2014. PMID: 24705490 Free article.

3

The BCL2 inhibitor ABT-199 significantly enhances imatinib-induced cell death in chronic myeloid leukemia progenitors.

Ko TK, Chuah CT, Huang JW, Ng KP, Ong ST. Ko TK, et al. Among authors: ong st. Oncotarget. 2014 Oct 15;5(19):9033-8. doi: 10.18632/oncotarget.1925. Oncotarget. 2014. PMID: 25333252 Free PMC article.

4

SRSF1 mediates cytokine-induced impaired imatinib sensitivity in chronic myeloid leukemia.

Sinnakannu JR, Lee KL, Cheng S, Li J, Yu M, Tan SP, Ong CCH, Li H, Than H, Anczuków-Camarda O, Krainer AR, Roca X, Rozen SG, Iqbal J, Yang H, Chuah C, Ong ST. Sinnakannu JR, et al. Among authors: ong cch, ong st. Leukemia. 2020 Jul;34(7):1787-1798. doi: 10.1038/s41375-020-0732-1. Epub 2020 Feb 12. Leukemia. 2020. PMID: 32051529 Free PMC article.

5

An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia.

Ko TK, Javed A, Lee KL, Pathiraja TN, Liu X, Malik S, Soh SX, Heng XT, Takahashi N, Tan JHJ, Bhatia R, Khng AJ, Chng WJ, Sia YY, Fruman DA, Ng KP, Chan ZE, Xie KJ, Hoi Q, Chan CX, Teo ASM, Velazquez Camacho O, Meah WY, Khor CC, Ong CTJ, Soon WJW, Tan P, Ng PC, Chuah C, Hillmer AM, Ong ST. Ko TK, et al. Among authors: ong ctj, ong st. Blood. 2020 Jun 25;135(26):2337-2353. doi: 10.1182/blood.2020004834. Blood. 2020. PMID: 32157296 Free article.

6

The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia.

Rauzan M, Chuah CT, Ko TK, Ong ST. Rauzan M, et al. Among authors: ong st. PLoS One. 2017 Mar 16;12(3):e0174107. doi: 10.1371/journal.pone.0174107. eCollection 2017. PLoS One. 2017. PMID: 28301600 Free PMC article.

7

BIM deletion polymorphism profiling complements prognostic values of risk scores in imatinib-treated Asian chronic myeloid leukemia patients.

Than H, Lye WK, Sng C, Allen JC Jr, Ong ST, Chuah C. Than H, et al. Among authors: ong st. Leuk Lymphoma. 2019 Jan;60(1):234-237. doi: 10.1080/10428194.2018.1461863. Epub 2018 Jun 19. Leuk Lymphoma. 2019. PMID: 29916288 No abstract available.

8

RCA2: a scalable supervised clustering algorithm that reduces batch effects in scRNA-seq data.

Schmidt F, Ranjan B, Lin QXX, Krishnan V, Joanito I, Honardoost MA, Nawaz Z, Venkatesh PN, Tan J, Rayan NA, Ong ST, Prabhakar S. Schmidt F, et al. Among authors: ong st. Nucleic Acids Res. 2021 Sep 7;49(15):8505-8519. doi: 10.1093/nar/gkab632. Nucleic Acids Res. 2021. PMID: 34320202 Free PMC article.

9

Integrating genetic and epigenetic factors in chronic myeloid leukemia risk assessment: toward gene expression-based biomarkers.

Krishnan V, Kim DDH, Hughes TP, Branford S, Ong ST. Krishnan V, et al. Among authors: ong st. Haematologica. 2022 Feb 1;107(2):358-370. doi: 10.3324/haematol.2021.279317. Haematologica. 2022. PMID: 34615339 Free PMC article. Review.

10

Validation and refinement of a RUNX1 mutation-associated gene expression signature in blast crisis chronic myeloid leukemia.

Lee KL, Ko TK, Saw NYL, Javed A, Hillmer AM, Chuah C, Krishnan V, Ong ST. Lee KL, et al. Among authors: ong st. Leukemia. 2022 Mar;36(3):892-896. doi: 10.1038/s41375-022-01508-1. Epub 2022 Feb 4. Leukemia. 2022. PMID: 35121847 Free PMC article. No abstract available.

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