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Microfluidics-free single-cell genomics with templated emulsification.
Clark IC, Fontanez KM, Meltzer RH, Xue Y, Hayford C, May-Zhang A, D'Amato C, Osman A, Zhang JQ, Hettige P, Ishibashi JSA, Delley CL, Weisgerber DW, Replogle JM, Jost M, Phong KT, Kennedy VE, Peretz CAC, Kim EA, Song S, Karlon W, Weissman JS, Smith CC, Gartner ZJ, Abate AR. Clark IC, et al. Among authors: weissman js. Nat Biotechnol. 2023 Nov;41(11):1557-1566. doi: 10.1038/s41587-023-01685-z. Epub 2023 Mar 6. Nat Biotechnol. 2023. PMID: 36879006 Free PMC article.
Nucleosomes impede Cas9 access to DNA in vivo and in vitro.
Horlbeck MA, Witkowsky LB, Guglielmi B, Replogle JM, Gilbert LA, Villalta JE, Torigoe SE, Tjian R, Weissman JS. Horlbeck MA, et al. Among authors: weissman js. Elife. 2016 Mar 17;5:e12677. doi: 10.7554/eLife.12677. Elife. 2016. PMID: 26987018 Free PMC article.
DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo.
Zubradt M, Gupta P, Persad S, Lambowitz AM, Weissman JS, Rouskin S. Zubradt M, et al. Among authors: weissman js. Nat Methods. 2017 Jan;14(1):75-82. doi: 10.1038/nmeth.4057. Epub 2016 Nov 7. Nat Methods. 2017. PMID: 27819661 Free PMC article.
CRISPR Approaches to Small Molecule Target Identification.
Jost M, Weissman JS. Jost M, et al. Among authors: weissman js. ACS Chem Biol. 2018 Feb 16;13(2):366-375. doi: 10.1021/acschembio.7b00965. Epub 2018 Jan 25. ACS Chem Biol. 2018. PMID: 29261286 Free PMC article. Review.
Molecular recording of mammalian embryogenesis.
Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS. Chan MM, et al. Among authors: weissman js. Nature. 2019 Jun;570(7759):77-82. doi: 10.1038/s41586-019-1184-5. Epub 2019 May 13. Nature. 2019. PMID: 31086336 Free PMC article.
Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.
Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B. Replogle JM, et al. Among authors: weissman js. Nat Biotechnol. 2020 Aug;38(8):954-961. doi: 10.1038/s41587-020-0470-y. Epub 2020 Mar 30. Nat Biotechnol. 2020. PMID: 32231336 Free PMC article.
543 results