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mRNA-1273 vaccinated inflammatory bowel disease patients receiving TNF inhibitors develop broad and robust SARS-CoV-2-specific CD8+ T cell responses.
van den Dijssel J, Duurland MC, Konijn VA, Kummer LY, Hagen RR, Kuijper LH, Wieske L, van Dam KP, Stalman EW, Steenhuis M, Geerdes DM, Mok JY, Kragten AH, Menage C, Koets L, Veldhuisen B, Verstegen NJ, van der Schoot CE, van Esch WJ, D'Haens GR, Löwenberg M, Volkers AG, Rispens T, Kuijpers TW, Eftimov F, van Gisbergen KP, van Ham SM, Ten Brinke A, van de Sandt CE; T2B! immunity against SARS-CoV-2 study group. van den Dijssel J, et al. Among authors: kragten ah. J Autoimmun. 2024 Apr;144:103175. doi: 10.1016/j.jaut.2024.103175. Epub 2024 Feb 21. J Autoimmun. 2024. PMID: 38387105 Free article.
A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair.
van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, Schärer OD, Luijsterburg MS. van den Heuvel D, et al. Among authors: kragten a. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2208860120. doi: 10.1073/pnas.2208860120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893274 Free PMC article.
Parallel detection of SARS-CoV-2 epitopes reveals dynamic immunodominance profiles of CD8+ T memory cells in convalescent COVID-19 donors.
van den Dijssel J, Hagen RR, de Jongh R, Steenhuis M, Rispens T, Geerdes DM, Mok JY, Kragten AH, Duurland MC, Verstegen NJ, van Ham SM, van Esch WJ, van Gisbergen KP, Hombrink P, Ten Brinke A, van de Sandt CE. van den Dijssel J, et al. Among authors: kragten ah. Clin Transl Immunology. 2022 Oct 14;11(10):e1423. doi: 10.1002/cti2.1423. eCollection 2022. Clin Transl Immunology. 2022. PMID: 36254196 Free PMC article.
XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair.
Blessing C, Apelt K, van den Heuvel D, Gonzalez-Leal C, Rother MB, van der Woude M, González-Prieto R, Yifrach A, Parnas A, Shah RG, Kuo TT, Boer DEC, Cai J, Kragten A, Kim HS, Schärer OD, Vertegaal ACO, Shah GM, Adar S, Lans H, van Attikum H, Ladurner AG, Luijsterburg MS. Blessing C, et al. Among authors: kragten a. Nat Commun. 2022 Aug 13;13(1):4762. doi: 10.1038/s41467-022-31820-4. Nat Commun. 2022. PMID: 35963869 Free PMC article.
A CSB-PAF1C axis restores processive transcription elongation after DNA damage repair.
van den Heuvel D, Spruijt CG, González-Prieto R, Kragten A, Paulsen MT, Zhou D, Wu H, Apelt K, van der Weegen Y, Yang K, Dijk M, Daxinger L, Marteijn JA, Vertegaal ACO, Ljungman M, Vermeulen M, Luijsterburg MS. van den Heuvel D, et al. Among authors: kragten a. Nat Commun. 2021 Feb 26;12(1):1342. doi: 10.1038/s41467-021-21520-w. Nat Commun. 2021. PMID: 33637760 Free PMC article.
ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients.
Apelt K, White SM, Kim HS, Yeo JE, Kragten A, Wondergem AP, Rooimans MA, González-Prieto R, Wiegant WW, Lunke S, Flanagan D, Pantaleo S, Quinlan C, Hardikar W, van Attikum H, Vertegaal ACO, Wilson BT, Wolthuis RMF, Schärer OD, Luijsterburg MS. Apelt K, et al. Among authors: kragten a. J Exp Med. 2021 Mar 1;218(3):e20200622. doi: 10.1084/jem.20200622. J Exp Med. 2021. PMID: 33315086 Free PMC article.
Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration.
Krouwels A, Iljas JD, Kragten AHM, Dhert WJA, Öner FC, Tryfonidou MA, Creemers LB. Krouwels A, et al. Among authors: kragten ahm. Int J Mol Sci. 2020 Apr 14;21(8):2720. doi: 10.3390/ijms21082720. Int J Mol Sci. 2020. PMID: 32295299 Free PMC article.
17 results