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Rapid rEcognition of COrticosteRoiD resistant or sensitive Sepsis (RECORDS): study protocol for a multicentre, placebo-controlled, biomarker-guided, adaptive Bayesian design basket trial.
Fleuriet J, Heming N, Meziani F, Reignier J, Declerq PL, Mercier E, Muller G, Colin G, Monnet X, Robine A, Siami S, Uhel F, Quenot JP, Plantefeve G, Badie J, Schneider F, Cerf C, Troché G, Monchi M, Mira JP, Francois B, Chevret S, Annane D; RECORDS consortium; CRICS TRIGGERSEP network. Fleuriet J, et al. Among authors: mira jp. BMJ Open. 2023 Mar 10;13(3):e066496. doi: 10.1136/bmjopen-2022-066496. BMJ Open. 2023. PMID: 36898751 Free PMC article.
The era of genomics: impact on sepsis clinical trial design.
Cariou A, Chiche JD, Charpentier J, Dhainaut JF, Mira JP. Cariou A, et al. Among authors: mira jp. Crit Care Med. 2002 May;30(5 Suppl):S341-8. doi: 10.1097/00003246-200205001-00026. Crit Care Med. 2002. PMID: 12004257 Review.
Design, conduct, and analysis of a multicenter, pharmacogenomic, biomarker study in matched patients with severe sepsis treated with or without drotrecogin Alfa (activated).
Annane D, Mira JP, Ware LB, Gordon AC, Sevransky J, Stüber F, Heagerty PJ, Wellman HF, Neira M, Mancini ADj, Russell JA. Annane D, et al. Among authors: mira jp. Ann Intensive Care. 2012 Jun 13;2(1):15. doi: 10.1186/2110-5820-2-15. Ann Intensive Care. 2012. PMID: 22694772 Free PMC article.
Evaluating the efficacy and safety of two doses of the polyclonal anti-tumor necrosis factor-α fragment antibody AZD9773 in adult patients with severe sepsis and/or septic shock: randomized, double-blind, placebo-controlled phase IIb study*.
Bernard GR, Francois B, Mira JP, Vincent JL, Dellinger RP, Russell JA, Larosa SP, Laterre PF, Levy MM, Dankner W, Schmitt N, Lindemann J, Wittebole X. Bernard GR, et al. Among authors: mira jp. Crit Care Med. 2014 Mar;42(3):504-11. doi: 10.1097/CCM.0000000000000043. Crit Care Med. 2014. PMID: 24335445 Clinical Trial.
369 results