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Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells.
Oltra SS, Colomo S, Sin L, Pérez-López M, Lázaro S, Molina-Crespo A, Choi KH, Ros-Pardo D, Martínez L, Morales S, González-Paramos C, Orantes A, Soriano M, Hernández A, Lluch A, Rojo F, Albanell J, Gómez-Puertas P, Ko JK, Sarrió D, Moreno-Bueno G. Oltra SS, et al. Among authors: molina crespo a. Cell Death Differ. 2023 May;30(5):1366-1381. doi: 10.1038/s41418-023-01143-y. Epub 2023 Mar 11. Cell Death Differ. 2023. PMID: 36899106 Free PMC article.
Gasdermin B over-expression modulates HER2-targeted therapy resistance by inducing protective autophagy through Rab7 activation.
Gámez-Chiachio M, Molina-Crespo Á, Ramos-Nebot C, Martinez-Val J, Martinez L, Gassner K, Llobet FJ, Soriano M, Hernandez A, Cordani M, Bernadó-Morales C, Diaz E, Rojo-Sebastian A, Triviño JC, Sanchez L, Rodríguez-Barrueco R, Arribas J, Llobet-Navás D, Sarrió D, Moreno-Bueno G. Gámez-Chiachio M, et al. Among authors: molina crespo a. J Exp Clin Cancer Res. 2022 Sep 26;41(1):285. doi: 10.1186/s13046-022-02497-w. J Exp Clin Cancer Res. 2022. PMID: 36163066 Free PMC article.
The multifaceted roles of gasdermins in cancer biology and oncologic therapies.
Sarrió D, Martínez-Val J, Molina-Crespo Á, Sánchez L, Moreno-Bueno G. Sarrió D, et al. Among authors: molina crespo a. Biochim Biophys Acta Rev Cancer. 2021 Dec;1876(2):188635. doi: 10.1016/j.bbcan.2021.188635. Epub 2021 Oct 14. Biochim Biophys Acta Rev Cancer. 2021. PMID: 34656686 Free article. Review.
Exosome-mimetic nanoplatforms for targeted cancer drug delivery.
Vázquez-Ríos AJ, Molina-Crespo Á, Bouzo BL, López-López R, Moreno-Bueno G, de la Fuente M. Vázquez-Ríos AJ, et al. Among authors: molina crespo a. J Nanobiotechnology. 2019 Jul 18;17(1):85. doi: 10.1186/s12951-019-0517-8. J Nanobiotechnology. 2019. PMID: 31319859 Free PMC article.
Intracellular Delivery of an Antibody Targeting Gasdermin-B Reduces HER2 Breast Cancer Aggressiveness.
Molina-Crespo Á, Cadete A, Sarrio D, Gámez-Chiachio M, Martinez L, Chao K, Olivera A, Gonella A, Díaz E, Palacios J, Dhal PK, Besev M, Rodríguez-Serrano M, García Bermejo ML, Triviño JC, Cano A, García-Fuentes M, Herzberg O, Torres D, Alonso MJ, Moreno-Bueno G. Molina-Crespo Á, et al. Clin Cancer Res. 2019 Aug 1;25(15):4846-4858. doi: 10.1158/1078-0432.CCR-18-2381. Epub 2019 May 7. Clin Cancer Res. 2019. PMID: 31064780
Gasdermin B expression predicts poor clinical outcome in HER2-positive breast cancer.
Hergueta-Redondo M, Sarrio D, Molina-Crespo Á, Vicario R, Bernadó-Morales C, Martínez L, Rojo-Sebastián A, Serra-Musach J, Mota A, Martínez-Ramírez Á, Castilla MÁ, González-Martin A, Pernas S, Cano A, Cortes J, Nuciforo PG, Peg V, Palacios J, Pujana MÁ, Arribas J, Moreno-Bueno G. Hergueta-Redondo M, et al. Among authors: molina crespo a. Oncotarget. 2016 Aug 30;7(35):56295-56308. doi: 10.18632/oncotarget.10787. Oncotarget. 2016. PMID: 27462779 Free PMC article.
Gasdermin-B promotes invasion and metastasis in breast cancer cells.
Hergueta-Redondo M, Sarrió D, Molina-Crespo Á, Megias D, Mota A, Rojo-Sebastian A, García-Sanz P, Morales S, Abril S, Cano A, Peinado H, Moreno-Bueno G. Hergueta-Redondo M, et al. Among authors: molina crespo a. PLoS One. 2014 Mar 27;9(3):e90099. doi: 10.1371/journal.pone.0090099. eCollection 2014. PLoS One. 2014. PMID: 24675552 Free PMC article.