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The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy.
Prins HAB, Crespo R, Lungu C, Rao S, Li L, Overmars RJ, Papageorgiou G, Mueller YM, Stoszko M, Hossain T, Kan TW, Rijnders BJA, Bax HI, van Gorp ECM, Nouwen JL, de Vries-Sluijs TEMS, Schurink CAM, de Mendonça Melo M, van Nood E, Colbers A, Burger D, Palstra RJ, van Kampen JJA, van de Vijver DAMC, Mesplède T, Katsikis PD, Gruters RA, Koch BCP, Verbon A, Mahmoudi T, Rokx C. Prins HAB, et al. Among authors: mahmoudi t. Sci Adv. 2023 Mar 17;9(11):eade6675. doi: 10.1126/sciadv.ade6675. Epub 2023 Mar 15. Sci Adv. 2023. PMID: 36921041 Free PMC article. Clinical Trial.
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.
Bisgrove DA, Mahmoudi T, Henklein P, Verdin E. Bisgrove DA, et al. Among authors: mahmoudi t. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13690-5. doi: 10.1073/pnas.0705053104. Epub 2007 Aug 9. Proc Natl Acad Sci U S A. 2007. PMID: 17690245 Free PMC article.
DNA looping induced by a transcriptional enhancer in vivo.
Petrascheck M, Escher D, Mahmoudi T, Verrijzer CP, Schaffner W, Barberis A. Petrascheck M, et al. Among authors: mahmoudi t. Nucleic Acids Res. 2005 Jul 7;33(12):3743-50. doi: 10.1093/nar/gki689. Print 2005. Nucleic Acids Res. 2005. PMID: 16002789 Free PMC article.
The kinase TNIK is an essential activator of Wnt target genes.
Mahmoudi T, Li VS, Ng SS, Taouatas N, Vries RG, Mohammed S, Heck AJ, Clevers H. Mahmoudi T, et al. EMBO J. 2009 Nov 4;28(21):3329-40. doi: 10.1038/emboj.2009.285. Epub 2009 Oct 8. EMBO J. 2009. PMID: 19816403 Free PMC article.
140 results