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The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy.
Prins HAB, Crespo R, Lungu C, Rao S, Li L, Overmars RJ, Papageorgiou G, Mueller YM, Stoszko M, Hossain T, Kan TW, Rijnders BJA, Bax HI, van Gorp ECM, Nouwen JL, de Vries-Sluijs TEMS, Schurink CAM, de Mendonça Melo M, van Nood E, Colbers A, Burger D, Palstra RJ, van Kampen JJA, van de Vijver DAMC, Mesplède T, Katsikis PD, Gruters RA, Koch BCP, Verbon A, Mahmoudi T, Rokx C. Prins HAB, et al. Among authors: mesplede t. Sci Adv. 2023 Mar 17;9(11):eade6675. doi: 10.1126/sciadv.ade6675. Epub 2023 Mar 15. Sci Adv. 2023. PMID: 36921041 Free PMC article. Clinical Trial.
Evolution of HIV integrase resistance mutations.
Quashie PK, Mesplède T, Wainberg MA. Quashie PK, et al. Among authors: mesplede t. Curr Opin Infect Dis. 2013 Feb;26(1):43-9. doi: 10.1097/QCO.0b013e32835ba81c. Curr Opin Infect Dis. 2013. PMID: 23242340 Review.
HIV-1 group O integrase displays lower enzymatic efficiency and higher susceptibility to raltegravir than HIV-1 group M subtype B integrase.
Depatureaux A, Quashie PK, Mesplède T, Han Y, Koubi H, Plantier JC, Oliveira M, Moisi D, Brenner B, Wainberg MA. Depatureaux A, et al. Among authors: mesplede t. Antimicrob Agents Chemother. 2014 Dec;58(12):7141-50. doi: 10.1128/AAC.03819-14. Epub 2014 Sep 15. Antimicrob Agents Chemother. 2014. PMID: 25224008 Free PMC article.
HIV Drug Resistance and the Advent of Integrase Inhibitors.
Quashie PK, Mesplède T, Wainberg MA. Quashie PK, et al. Among authors: mesplede t. Curr Infect Dis Rep. 2013 Feb;15(1):85-100. doi: 10.1007/s11908-012-0305-1. Curr Infect Dis Rep. 2013. PMID: 23180144
Resistance to HIV integrase inhibitors.
Mesplède T, Quashie PK, Wainberg MA. Mesplède T, et al. Curr Opin HIV AIDS. 2012 Sep;7(5):401-8. doi: 10.1097/COH.0b013e328356db89. Curr Opin HIV AIDS. 2012. PMID: 22789986 Review.
105 results