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The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy.
Prins HAB, Crespo R, Lungu C, Rao S, Li L, Overmars RJ, Papageorgiou G, Mueller YM, Stoszko M, Hossain T, Kan TW, Rijnders BJA, Bax HI, van Gorp ECM, Nouwen JL, de Vries-Sluijs TEMS, Schurink CAM, de Mendonça Melo M, van Nood E, Colbers A, Burger D, Palstra RJ, van Kampen JJA, van de Vijver DAMC, Mesplède T, Katsikis PD, Gruters RA, Koch BCP, Verbon A, Mahmoudi T, Rokx C. Prins HAB, et al. Among authors: rao s. Sci Adv. 2023 Mar 17;9(11):eade6675. doi: 10.1126/sciadv.ade6675. Epub 2023 Mar 15. Sci Adv. 2023. PMID: 36921041 Free PMC article. Clinical Trial.
Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models.
Clark MP, Huynh T, Rao S, Mackiewicz L, Mason H, Romal S, Stutz MD, Ahn SH, Earnest L, Sozzi V, Littlejohn M, Tran BM, Wiedemann N, Vincan E, Torresi J, Netter HJ, Mahmoudi T, Revill P, Pellegrini M, Ebert G. Clark MP, et al. Among authors: rao s. Cell Death Dis. 2021 Jun 23;12(7):641. doi: 10.1038/s41419-021-03924-0. Cell Death Dis. 2021. PMID: 34162831 Free PMC article.
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma.
De Crignis E, Hossain T, Romal S, Carofiglio F, Moulos P, Khalid MM, Rao S, Bazrafshan A, Verstegen MM, Pourfarzad F, Koutsothanassis C, Gehart H, Kan TW, Palstra RJ, Boucher C, IJzermans JN, Huch M, Boj SF, Vries R, Clevers H, van der Laan LJ, Hatzis P, Mahmoudi T. De Crignis E, et al. Among authors: rao s. Elife. 2021 Jul 30;10:e60747. doi: 10.7554/eLife.60747. Elife. 2021. PMID: 34328417 Free PMC article.
HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency.
Crespo R, Rao S, Mahmoudi T. Crespo R, et al. Among authors: rao s. Front Cell Infect Microbiol. 2022 Jun 14;12:855092. doi: 10.3389/fcimb.2022.855092. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35774399 Free PMC article. Review.
PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency.
Crespo R, Ne E, Reinders J, Meier JIJ, Li C, Jansen S, Górska A, Koçer S, Kan TW, Doff W, Dekkers D, Demmers J, Palstra RJ, Rao S, Mahmoudi T. Crespo R, et al. Among authors: rao s. iScience. 2024 Feb 6;27(3):109152. doi: 10.1016/j.isci.2024.109152. eCollection 2024 Mar 15. iScience. 2024. PMID: 38384833 Free PMC article.
9,396 results