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Structural basis of selective cannabinoid CB2 receptor activation.
Li X, Chang H, Bouma J, de Paus LV, Mukhopadhyay P, Paloczi J, Mustafa M, van der Horst C, Kumar SS, Wu L, Yu Y, van den Berg RJBHN, Janssen APA, Lichtman A, Liu ZJ, Pacher P, van der Stelt M, Heitman LH, Hua T. Li X, et al. Among authors: heitman lh. Nat Commun. 2023 Mar 15;14(1):1447. doi: 10.1038/s41467-023-37112-9. Nat Commun. 2023. PMID: 36922494 Free PMC article.
The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor.
Gutiérrez-de-Terán H, Massink A, Rodríguez D, Liu W, Han GW, Joseph JS, Katritch I, Heitman LH, Xia L, Ijzerman AP, Cherezov V, Katritch V, Stevens RC. Gutiérrez-de-Terán H, et al. Among authors: heitman lh. Structure. 2013 Dec 3;21(12):2175-85. doi: 10.1016/j.str.2013.09.020. Epub 2013 Nov 7. Structure. 2013. PMID: 24210756 Free PMC article.
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters.
Dvorak V, Wiedmer T, Ingles-Prieto A, Altermatt P, Batoulis H, Bärenz F, Bender E, Digles D, Dürrenberger F, Heitman LH, IJzerman AP, Kell DB, Kickinger S, Körzö D, Leippe P, Licher T, Manolova V, Rizzetto R, Sassone F, Scarabottolo L, Schlessinger A, Schneider V, Sijben HJ, Steck AL, Sundström H, Tremolada S, Wilhelm M, Wright Muelas M, Zindel D, Steppan CM, Superti-Furga G. Dvorak V, et al. Among authors: heitman lh. Front Pharmacol. 2021 Aug 10;12:722889. doi: 10.3389/fphar.2021.722889. eCollection 2021. Front Pharmacol. 2021. PMID: 34447313 Free PMC article. Review.
Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists.
Junker A, Kokornaczyk AK, Zweemer AJ, Frehland B, Schepmann D, Yamaguchi J, Itami K, Faust A, Hermann S, Wagner S, Schäfers M, Koch M, Weiss C, Heitman LH, Kopka K, Wünsch B. Junker A, et al. Among authors: heitman lh. Org Biomol Chem. 2015 Feb 28;13(8):2407-22. doi: 10.1039/c4ob02397h. Org Biomol Chem. 2015. PMID: 25566983
Synthesis and evaluation of homo-bivalent GnRHR ligands.
Bonger KM, van den Berg RJ, Heitman LH, IJzerman AP, Oosterom J, Timmers CM, Overkleeft HS, van der Marel GA. Bonger KM, et al. Among authors: heitman lh. Bioorg Med Chem. 2007 Jul 15;15(14):4841-56. doi: 10.1016/j.bmc.2007.04.065. Epub 2007 May 6. Bioorg Med Chem. 2007. PMID: 17517510
146 results