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Structural basis of selective cannabinoid CB2 receptor activation.
Li X, Chang H, Bouma J, de Paus LV, Mukhopadhyay P, Paloczi J, Mustafa M, van der Horst C, Kumar SS, Wu L, Yu Y, van den Berg RJBHN, Janssen APA, Lichtman A, Liu ZJ, Pacher P, van der Stelt M, Heitman LH, Hua T. Li X, et al. Among authors: mukhopadhyay p. Nat Commun. 2023 Mar 15;14(1):1447. doi: 10.1038/s41467-023-37112-9. Nat Commun. 2023. PMID: 36922494 Free PMC article.
The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.
Mukhopadhyay P, Baggelaar M, Erdelyi K, Cao Z, Cinar R, Fezza F, Ignatowska-Janlowska B, Wilkerson J, van Gils N, Hansen T, Ruben M, Soethoudt M, Heitman L, Kunos G, Maccarrone M, Lichtman A, Pacher P, Van der Stelt M. Mukhopadhyay P, et al. Br J Pharmacol. 2016 Feb;173(3):446-58. doi: 10.1111/bph.13338. Epub 2016 Jan 15. Br J Pharmacol. 2016. PMID: 26398481 Free PMC article.
Interplay of Liver-Heart Inflammatory Axis and Cannabinoid 2 Receptor Signaling in an Experimental Model of Hepatic Cardiomyopathy.
Matyas C, Erdelyi K, Trojnar E, Zhao S, Varga ZV, Paloczi J, Mukhopadhyay P, Nemeth BT, Haskó G, Cinar R, Rodrigues RM, Ait Ahmed Y, Gao B, Pacher P. Matyas C, et al. Among authors: mukhopadhyay p. Hepatology. 2020 Apr;71(4):1391-1407. doi: 10.1002/hep.30916. Epub 2020 Jan 24. Hepatology. 2020. PMID: 31469200 Free PMC article.
Cannabinoid-2 receptor activation ameliorates hepatorenal syndrome.
Trojnar E, Erdelyi K, Matyas C, Zhao S, Paloczi J, Mukhopadhyay P, Varga ZV, Hasko G, Pacher P. Trojnar E, et al. Among authors: mukhopadhyay p. Free Radic Biol Med. 2020 May 20;152:540-550. doi: 10.1016/j.freeradbiomed.2019.11.027. Epub 2019 Nov 23. Free Radic Biol Med. 2020. PMID: 31770583
A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.
Horváth B, Magid L, Mukhopadhyay P, Bátkai S, Rajesh M, Park O, Tanchian G, Gao RY, Goodfellow CE, Glass M, Mechoulam R, Pacher P. Horváth B, et al. Among authors: mukhopadhyay p. Br J Pharmacol. 2012 Apr;165(8):2462-78. doi: 10.1111/j.1476-5381.2011.01381.x. Br J Pharmacol. 2012. PMID: 21449982 Free PMC article.
618 results