Davies P - Search Results

1

S-acylation stabilizes ligand-induced receptor kinase complex formation during plant pattern-triggered immune signaling.

Hurst CH, Turnbull D, Xhelilaj K, Myles S, Pflughaupt RL, Kopischke M, Davies P, Jones S, Robatzek S, Zipfel C, Gronnier J, Hemsley PA. Hurst CH, et al. Among authors: davies p. Curr Biol. 2023 Apr 24;33(8):1588-1596.e6. doi: 10.1016/j.cub.2023.02.065. Epub 2023 Mar 15. Curr Biol. 2023. PMID: 36924767 Free article.

2

CDK1 and CDK2 regulate NICD1 turnover and the periodicity of the segmentation clock.

Carrieri FA, Murray PJ, Ditsova D, Ferris MA, Davies P, Dale JK. Carrieri FA, et al. Among authors: davies p. EMBO Rep. 2019 Jul;20(7):e46436. doi: 10.15252/embr.201846436. Epub 2019 Apr 17. EMBO Rep. 2019. PMID: 31267714 Free PMC article.

3

Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity.

Houde VP, Ritorto MS, Gourlay R, Varghese J, Davies P, Shpiro N, Sakamoto K, Alessi DR. Houde VP, et al. Among authors: davies p. Biochem J. 2014 Feb 15;458(1):41-56. doi: 10.1042/BJ20131324. Biochem J. 2014. PMID: 24295069 Free PMC article.

4

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase.

Bago R, Malik N, Munson MJ, Prescott AR, Davies P, Sommer E, Shpiro N, Ward R, Cross D, Ganley IG, Alessi DR. Bago R, et al. Among authors: davies p. Biochem J. 2014 Nov 1;463(3):413-27. doi: 10.1042/BJ20140889. Biochem J. 2014. PMID: 25177796 Free PMC article.

5

Photoactivatable Prodrugs of Antimelanoma Agent Vemurafenib.

Horbert R, Pinchuk B, Davies P, Alessi D, Peifer C. Horbert R, et al. Among authors: davies p. ACS Chem Biol. 2015 Sep 18;10(9):2099-107. doi: 10.1021/acschembio.5b00174. Epub 2015 Jul 10. ACS Chem Biol. 2015. PMID: 26061392

6

High-Throughput MALDI-TOF Mass Spectrometry-Based Deubiquitylating Enzyme Assay for Drug Discovery.

De Cesare V, Davies P. De Cesare V, et al. Among authors: davies p. Methods Mol Biol. 2023;2591:123-134. doi: 10.1007/978-1-0716-2803-4_8. Methods Mol Biol. 2023. PMID: 36350546

7

Design and high-throughput implementation of MALDI-TOF/MS-based assays for Parkin E3 ligase activity.

Traynor R, Moran J, Stevens M, Antico O, Knebel A, Behrouz B, Merchant K, Hastie CJ, Davies P, Muqit MMK, De Cesare V. Traynor R, et al. Among authors: davies p. Cell Rep Methods. 2024 Feb 26;4(2):100712. doi: 10.1016/j.crmeth.2024.100712. Epub 2024 Feb 20. Cell Rep Methods. 2024. PMID: 38382522 Free PMC article.

8

Development of a highly potent and selective degrader of LRRK2.

Hatcher JM, Zwirek M, Sarhan AR, Vatsan PS, Tonelli F, Alessi DR, Davies P, Gray NS. Hatcher JM, et al. Among authors: davies p. Bioorg Med Chem Lett. 2023 Oct 1;94:129449. doi: 10.1016/j.bmcl.2023.129449. Epub 2023 Aug 15. Bioorg Med Chem Lett. 2023. PMID: 37591317

9

Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies.

Davies P, Hinkle KM, Sukar NN, Sepulveda B, Mesias R, Serrano G, Alessi DR, Beach TG, Benson DL, White CL, Cowell RM, Das SS, West AB, Melrose HL. Davies P, et al. Biochem J. 2013 Jul 1;453(1):101-13. doi: 10.1042/BJ20121742. Biochem J. 2013. PMID: 23560750 Free PMC article.

10

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

Steger M, Tonelli F, Ito G, Davies P, Trost M, Vetter M, Wachter S, Lorentzen E, Duddy G, Wilson S, Baptista MA, Fiske BK, Fell MJ, Morrow JA, Reith AD, Alessi DR, Mann M. Steger M, et al. Among authors: davies p. Elife. 2016 Jan 29;5:e12813. doi: 10.7554/eLife.12813. Elife. 2016. PMID: 26824392 Free PMC article.

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