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The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time.
Shahid A, MacLennan S, Jones BR, Sudderuddin H, Dang Z, Cobarrubias K, Duncan MC, Kinloch NN, Dapp MJ, Archin NM, Fischl MA, Ofotokun I, Adimora A, Gange S, Aouizerat B, Kuniholm MH, Kassaye S, Mullins JI, Goldstein H, Joy JB, Anastos K, Brumme ZL; MACS/WIHS combined cohort study (MWCSS). Shahid A, et al. J Virol. 2024 Feb 20;98(2):e0165523. doi: 10.1128/jvi.01655-23. Epub 2024 Jan 12. J Virol. 2024. PMID: 38214547 Free PMC article.
Microfluidic Isolation of Neuronal-Enriched Extracellular Vesicles Shows Distinct and Common Neurological Proteins in Long COVID, HIV Infection and Alzheimer's Disease.
Pulliam L, Sun B, McCafferty E, Soper SA, Witek MA, Hu M, Ford JM, Song S, Kapogiannis D, Glesby MJ, Merenstein D, Tien PC, Freasier H, French A, McKay H, Diaz MM, Ofotokun I, Lake JE, Margolick JB, Kim EY, Levine SR, Fischl MA, Li W, Martinson J, Tang N. Pulliam L, et al. Among authors: margolick jb. Int J Mol Sci. 2024 Mar 29;25(7):3830. doi: 10.3390/ijms25073830. Int J Mol Sci. 2024. PMID: 38612641 Free PMC article.
Sleep-Disordered Breathing and Prevalent Hypertension in Men With and Without HIV.
Punjabi NM, Brown TT, Abreu AR, Aurora RN, Patel SR, Stosor V, Cho JH, D'Souza G, Wallace D, Margolick JB. Punjabi NM, et al. Among authors: margolick jb. J Acquir Immune Defic Syndr. 2023 Dec 1;94(4):349-354. doi: 10.1097/QAI.0000000000003276. J Acquir Immune Defic Syndr. 2023. PMID: 37643405
Mild HIV-specific selective forces overlaying natural CD4+ T cell dynamics explain the clonality and decay dynamics of HIV reservoir cells.
Reeves DB, Rigau DN, Romero A, Zhang H, Simonetti FR, Varriale J, Hoh R, Zhang L, Smith KN, Montaner LJ, Rubin LH, Gange SJ, Roan NR, Tien PC, Margolick JB, Peluso MJ, Deeks SG, Schiffer JT, Siliciano JD, Siliciano RF, Antar AAR. Reeves DB, et al. Among authors: margolick jb. medRxiv [Preprint]. 2024 Feb 15:2024.02.13.24302704. doi: 10.1101/2024.02.13.24302704. medRxiv. 2024. PMID: 38405967 Free PMC article. Preprint.
366 results