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Upregulation of the ERRγ-VDAC1 axis underlies the molecular pathogenesis of pancreatitis.
Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2219644120. doi: 10.1073/pnas.2219644120. Epub 2023 May 8.
Proc Natl Acad Sci U S A. 2023.
PMID: 37155882
Free PMC article.
Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease.
Thoudam T, Chanda D, Lee JY, Jung MK, Sinam IS, Kim BG, Park BY, Kwon WH, Kim HJ, Kim M, Lim CW, Lee H, Huh YH, Miller CA, Saxena R, Skill NJ, Huda N, Kusumanchi P, Ma J, Yang Z, Kim MJ, Mun JY, Harris RA, Jeon JH, Liangpunsakul S, Lee IK.
Thoudam T, et al. Among authors: sinam is.
Nat Commun. 2023 Mar 27;14(1):1703. doi: 10.1038/s41467-023-37214-4.
Nat Commun. 2023.
PMID: 36973273
Free PMC article.
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The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4.
Kim MJ, Sinam IS, Siddique Z, Jeon JH, Lee IK.
Kim MJ, et al. Among authors: sinam is.
Diabetes Metab J. 2023 Mar;47(2):153-163. doi: 10.4093/dmj.2022.0305. Epub 2023 Jan 12.
Diabetes Metab J. 2023.
PMID: 36635027
Free PMC article.
Review.
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Pyruvate dehydrogenase kinase 4 promotes ubiquitin-proteasome system-dependent muscle atrophy.
Sinam IS, Chanda D, Thoudam T, Kim MJ, Kim BG, Kang HJ, Lee JY, Baek SH, Kim SY, Shim BJ, Ryu D, Jeon JH, Lee IK.
Sinam IS, et al.
J Cachexia Sarcopenia Muscle. 2022 Dec;13(6):3122-3136. doi: 10.1002/jcsm.13100. Epub 2022 Oct 19.
J Cachexia Sarcopenia Muscle. 2022.
PMID: 36259412
Free PMC article.
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Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status.
Thoudam T, Chanda D, Sinam IS, Kim BG, Kim MJ, Oh CJ, Lee JY, Kim MJ, Park SY, Lee SY, Jung MK, Mun JY, Harris RA, Ishihara N, Jeon JH, Lee IK.
Thoudam T, et al. Among authors: sinam is.
Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2120157119. doi: 10.1073/pnas.2120157119. Epub 2022 Aug 15.
Proc Natl Acad Sci U S A. 2022.
PMID: 35969774
Free PMC article.
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