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Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells.
Missinato MA, Murphy S, Lynott M, Yu MS, Kervadec A, Chang YL, Kannan S, Loreti M, Lee C, Amatya P, Tanaka H, Huang CT, Puri PL, Kwon C, Adams PD, Qian L, Sacco A, Andersen P, Colas AR. Missinato MA, et al. Among authors: colas ar. Nat Commun. 2023 Mar 27;14(1):1709. doi: 10.1038/s41467-023-37256-8. Nat Commun. 2023. PMID: 36973293 Free PMC article.
Id genes are essential for early heart formation.
Cunningham TJ, Yu MS, McKeithan WL, Spiering S, Carrette F, Huang CT, Bushway PJ, Tierney M, Albini S, Giacca M, Mano M, Puri PL, Sacco A, Ruiz-Lozano P, Riou JF, Umbhauer M, Duester G, Mercola M, Colas AR. Cunningham TJ, et al. Among authors: colas ar. Genes Dev. 2017 Jul 1;31(13):1325-1338. doi: 10.1101/gad.300400.117. Epub 2017 Aug 9. Genes Dev. 2017. PMID: 28794185 Free PMC article.
Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors.
El Harane N, Kervadec A, Bellamy V, Pidial L, Neametalla HJ, Perier MC, Lima Correa B, Thiébault L, Cagnard N, Duché A, Brunaud C, Lemitre M, Gauthier J, Bourdillon AT, Renault MP, Hovhannisyan Y, Paiva S, Colas AR, Agbulut O, Hagège A, Silvestre JS, Menasché P, Renault NKE. El Harane N, et al. Among authors: colas ar. Eur Heart J. 2018 May 21;39(20):1835-1847. doi: 10.1093/eurheartj/ehy012. Eur Heart J. 2018. PMID: 29420830 Free PMC article.
Silencing of CCR4-NOT complex subunits affects heart structure and function.
Elmén L, Volpato CB, Kervadec A, Pineda S, Kalvakuri S, Alayari NN, Foco L, Pramstaller PP, Ocorr K, Rossini A, Cammarato A, Colas AR, Hicks AA, Bodmer R. Elmén L, et al. Among authors: colas ar. Dis Model Mech. 2020 Jul 20;13(7):dmm044727. doi: 10.1242/dmm.044727. Dis Model Mech. 2020. PMID: 32471864 Free PMC article.
Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome.
Theis JL, Vogler G, Missinato MA, Li X, Nielsen T, Zeng XI, Martinez-Fernandez A, Walls SM, Kervadec A, Kezos JN, Birker K, Evans JM, O'Byrne MM, Fogarty ZC, Terzic A, Grossfeld P, Ocorr K, Nelson TJ, Olson TM, Colas AR, Bodmer R. Theis JL, et al. Among authors: colas ar. Elife. 2020 Oct 2;9:e59554. doi: 10.7554/eLife.59554. Elife. 2020. PMID: 33006316 Free PMC article.
PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2.
Murphy SA, Miyamoto M, Kervadec A, Kannan S, Tampakakis E, Kambhampati S, Lin BL, Paek S, Andersen P, Lee DI, Zhu R, An SS, Kass DA, Uosaki H, Colas AR, Kwon C. Murphy SA, et al. Among authors: colas ar. Nat Commun. 2021 Mar 12;12(1):1648. doi: 10.1038/s41467-021-21957-z. Nat Commun. 2021. PMID: 33712605 Free PMC article.
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