Kschonsak M - Search Results

1

Cryo-EM reveals an unprecedented binding site for Na_V1.7 inhibitors enabling rational design of potent hybrid inhibitors.

Kschonsak M, Jao CC, Arthur CP, Rohou AL, Bergeron P, Ortwine DF, McKerrall SJ, Hackos DH, Deng L, Chen J, Li T, Dragovich PS, Volgraf M, Wright MR, Payandeh J, Ciferri C, Tellis JC. Kschonsak M, et al. Elife. 2023 Mar 28;12:e84151. doi: 10.7554/eLife.84151. Elife. 2023. PMID: 36975198 Free PMC article.

2

Ternary complex dissociation kinetics contribute to mutant-selective EGFR degradation.

Rosenberg SC, Shanahan F, Yamazoe S, Kschonsak M, Zeng YJ, Lee J, Plise E, Yen I, Rose CM, Quinn JG, Gazzard LJ, Walters BT, Kirkpatrick DS, Staben ST, Foster SA, Malek S. Rosenberg SC, et al. Among authors: kschonsak m. Cell Chem Biol. 2023 Feb 8:S2451-9456(23)00030-2. doi: 10.1016/j.chembiol.2023.01.007. Online ahead of print. Cell Chem Biol. 2023. PMID: 36773603 Free article.

3

A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.

Shaltiel IA, Datta S, Lecomte L, Hassler M, Kschonsak M, Bravo S, Stober C, Ormanns J, Eustermann S, Haering CH. Shaltiel IA, et al. Among authors: kschonsak m. Science. 2022 Jun 3;376(6597):1087-1094. doi: 10.1126/science.abm4012. Epub 2022 Jun 2. Science. 2022. PMID: 35653469

4

Structure-guided unlocking of Na_X reveals a non-selective tetrodotoxin-sensitive cation channel.

Noland CL, Chua HC, Kschonsak M, Heusser SA, Braun N, Chang T, Tam C, Tang J, Arthur CP, Ciferri C, Pless SA, Payandeh J. Noland CL, et al. Among authors: kschonsak m. Nat Commun. 2022 Mar 17;13(1):1416. doi: 10.1038/s41467-022-28984-4. Nat Commun. 2022. PMID: 35301303 Free PMC article.

5

Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.

Kschonsak M, Johnson MC, Schelling R, Green EM, Rougé L, Ho H, Patel N, Kilic C, Kraft E, Arthur CP, Rohou AL, Comps-Agrar L, Martinez-Martin N, Perez L, Payandeh J, Ciferri C. Kschonsak M, et al. Sci Adv. 2022 Mar 11;8(10):eabm2536. doi: 10.1126/sciadv.abm2536. Epub 2022 Mar 11. Sci Adv. 2022. PMID: 35275719 Free PMC article.

6

Structural architecture of the human NALCN channelosome.

Kschonsak M, Chua HC, Weidling C, Chakouri N, Noland CL, Schott K, Chang T, Tam C, Patel N, Arthur CP, Leitner A, Ben-Johny M, Ciferri C, Pless SA, Payandeh J. Kschonsak M, et al. Nature. 2022 Mar;603(7899):180-186. doi: 10.1038/s41586-021-04313-5. Epub 2021 Dec 20. Nature. 2022. PMID: 34929720

7

Up-regulation of ubiquitin-proteasome activity upon loss of NatA-dependent N-terminal acetylation.

Kats I, Reinbold C, Kschonsak M, Khmelinskii A, Armbruster L, Ruppert T, Knop M. Kats I, et al. Among authors: kschonsak m. Life Sci Alliance. 2021 Nov 11;5(2):e202000730. doi: 10.26508/lsa.202000730. Print 2022 Feb. Life Sci Alliance. 2021. PMID: 34764209 Free PMC article.

8

Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry.

Kschonsak M, Rougé L, Arthur CP, Hoangdung H, Patel N, Kim I, Johnson MC, Kraft E, Rohou AL, Gill A, Martinez-Martin N, Payandeh J, Ciferri C. Kschonsak M, et al. Cell. 2021 Mar 4;184(5):1232-1244.e16. doi: 10.1016/j.cell.2021.01.036. Epub 2021 Feb 23. Cell. 2021. PMID: 33626330 Free article.

9

Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients.

Fernando TM, Piskol R, Bainer R, Sokol ES, Trabucco SE, Zhang Q, Trinh H, Maund S, Kschonsak M, Chaudhuri S, Modrusan Z, Januario T, Yauch RL. Fernando TM, et al. Among authors: kschonsak m. Nat Commun. 2020 Nov 3;11(1):5551. doi: 10.1038/s41467-020-19402-8. Nat Commun. 2020. PMID: 33144586 Free PMC article.

10

Structure of the human sodium leak channel NALCN.

Kschonsak M, Chua HC, Noland CL, Weidling C, Clairfeuille T, Bahlke OØ, Ameen AO, Li ZR, Arthur CP, Ciferri C, Pless SA, Payandeh J. Kschonsak M, et al. Nature. 2020 Nov;587(7833):313-318. doi: 10.1038/s41586-020-2570-8. Epub 2020 Jul 22. Nature. 2020. PMID: 32698188

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