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Necroptosis blockade prevents lung injury in severe influenza.
Gautam A, Boyd DF, Nikhar S, Zhang T, Siokas I, Van de Velde LA, Gaevert J, Meliopoulos V, Thapa B, Rodriguez DA, Cai KQ, Yin C, Schnepf D, Beer J, DeAntoneo C, Williams RM, Shubina M, Livingston B, Zhang D, Andrake MD, Lee S, Boda R, Duddupudi AL, Crawford JC, Vogel P, Loch C, Schwemmle M, Fritz LC, Schultz-Cherry S, Green DR, Cuny GD, Thomas PG, Degterev A, Balachandran S. Gautam A, et al. Among authors: cai kq. Nature. 2024 Apr;628(8009):835-843. doi: 10.1038/s41586-024-07265-8. Epub 2024 Apr 10. Nature. 2024. PMID: 38600381
Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and Enhanced Self-Renewal Potential.
Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Graña X, Hamilton KE, Whelan KA. Klochkova A, et al. Among authors: cai kq. Cell Mol Gastroenterol Hepatol. 2024 Mar 5;18(1):15-40. doi: 10.1016/j.jcmgh.2024.02.018. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38452871 Free PMC article.
Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer.
Murayama T, Nakayama J, Jiang X, Miyata K, Morris AD, Cai KQ, Prasad RM, Ma X, Efimov A, Belani N, Gerstein ER, Tan Y, Zhou Y, Kim W, Maruyama R, Campbell KS, Chen L, Yang Y, Balachandran S, Cañadas I. Murayama T, et al. Among authors: cai kq. Cancer Discov. 2024 Mar 1;14(3):468-491. doi: 10.1158/2159-8290.CD-23-0486. Cancer Discov. 2024. PMID: 38189443 Free PMC article.
SAR-096: Phase II Clinical Trial of Ribociclib in Combination with Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS).
Movva S, Matloob S, Handorf EA, Choy E, Merriam P, Flieder DB, Cai KQ, Zhou Y, Tetzlaff ED, Pagan C, Barker E, Veggeberg R, Zumpano D, Rink L, von Mehren M, George S. Movva S, et al. Among authors: cai kq. Clin Cancer Res. 2024 Jan 17;30(2):315-322. doi: 10.1158/1078-0432.CCR-23-2469. Clin Cancer Res. 2024. PMID: 37967116 Clinical Trial.
Autophagy contributes to homeostasis in esophageal epithelium where high autophagic vesicle content marks basal cells with limited proliferation and enhanced self-renewal potential.
Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Hamilton KE, Whelan KA. Klochkova A, et al. Among authors: cai kq. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558614. doi: 10.1101/2023.09.20.558614. bioRxiv. 2023. PMID: 37781581 Free PMC article. Updated. Preprint.
Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6).
Ogier C, Solomon AMC, Lu Z, Recoules L, Klochkova A, Gabitova-Cornell L, Bayarmagnai B, Restifo D, Surumbayeva A, Vendramini-Costa DB, Deneka AY, Francescone R, Lilly AC, Sipman A, Gardiner JC, Luong T, Franco-Barraza J, Ibeme N, Cai KQ, Einarson MB, Nicolas E, Efimov A, Megill E, Snyder NW, Bousquet C, Cros J, Zhou Y, Golemis EA, Gligorijevic B, Soboloff J, Fuchs SY, Cukierman E, Astsaturov I. Ogier C, et al. Among authors: cai kq. bioRxiv [Preprint]. 2023 Sep 17:2023.09.15.557802. doi: 10.1101/2023.09.15.557802. bioRxiv. 2023. PMID: 37745612 Free PMC article. Preprint.
124 results