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Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1.
Ruddiman CA, Peckham R, Luse MA, Chen YL, Kuppusamy M, Corliss BA, Hall PJ, Lin CJ, Peirce SM, Sonkusare SK, Mecham RP, Wagenseil JE, Isakson BE. Ruddiman CA, et al. Among authors: mecham rp. JCI Insight. 2023 May 8;8(9):e165715. doi: 10.1172/jci.insight.165715. JCI Insight. 2023. PMID: 37014698 Free PMC article.
Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2).
Bodmer NK, Knutsen RH, Roth RA, Castile RM, Brodt MD, Gierasch CM, Broekelmann TJ, Gibson MA, Haspel JA, Lake SP, Koenitzer JR, Brody SL, Silva MJ, Mecham RP, Ornitz DM. Bodmer NK, et al. Among authors: mecham rp. Dev Dyn. 2024 Feb;253(2):233-254. doi: 10.1002/dvdy.651. Epub 2023 Sep 9. Dev Dyn. 2024. PMID: 37688792 Review.
Author Correction: SVEP1 is an endogenous ligand for the orphan receptor PEAR1.
Elenbaas JS, Pudupakkam U, Ashworth KJ, Kang CJ, Patel V, Santana K, Jung IH, Lee PC, Burks KH, Amrute JM, Mecham RP, Halabi CM, Alisio A, Di Paola J, Stitziel NO. Elenbaas JS, et al. Among authors: mecham rp. Nat Commun. 2023 Mar 17;14(1):1511. doi: 10.1038/s41467-023-37005-x. Nat Commun. 2023. PMID: 36932061 Free PMC article. No abstract available.
SVEP1 is an endogenous ligand for the orphan receptor PEAR1.
Elenbaas JS, Pudupakkam U, Ashworth KJ, Kang CJ, Patel V, Santana K, Jung IH, Lee PC, Burks KH, Amrute JM, Mecham RP, Halabi CM, Alisio A, Di Paola J, Stitziel NO. Elenbaas JS, et al. Among authors: mecham rp. Nat Commun. 2023 Feb 15;14(1):850. doi: 10.1038/s41467-023-36486-0. Nat Commun. 2023. PMID: 36792666 Free PMC article.
LTBP1 promotes fibrillin incorporation into the extracellular matrix.
Przyklenk M, Georgieva VS, Metzen F, Mostert S, Kobbe B, Callewaert B, Sengle G, Brachvogel B, Mecham RP, Paulsson M, Wagener R, Koch M, Schiavinato A. Przyklenk M, et al. Among authors: mecham rp. Matrix Biol. 2022 Jun;110:60-75. doi: 10.1016/j.matbio.2022.04.004. Epub 2022 Apr 19. Matrix Biol. 2022. PMID: 35452817
291 results