Rosenkilde MM - Search Results

1

Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization.

Kjær VMS, Daugvilaite V, Stepniewski TM, Madsen CM, Jørgensen AS, Bhuskute KR, Inoue A, Ulven T, Benned-Jensen T, Hjorth SA, Hjortø GM, Moo EV, Selent J, Rosenkilde MM. Kjær VMS, et al. Among authors: rosenkilde mm. Sci Signal. 2023 Apr 4;16(779):eabl4283. doi: 10.1126/scisignal.abl4283. Epub 2023 Apr 4. Sci Signal. 2023. PMID: 37014928

2

Mutations along transmembrane segment II of the NK-1 receptor affect substance P competition with non-peptide antagonists but not substance P binding.

Rosenkilde MM, Cahir M, Gether U, Hjorth SA, Schwartz TW. Rosenkilde MM, et al. J Biol Chem. 1994 Nov 11;269(45):28160-4. J Biol Chem. 1994. PMID: 7525569 Free article.

3

How receptor mutagenesis may confirm or confuse receptor classification.

Schwartz TW, Perlman S, Rosenkilde MM, Hjorth SA. Schwartz TW, et al. Among authors: rosenkilde mm. Ann N Y Acad Sci. 1997 May 30;812:71-84. doi: 10.1111/j.1749-6632.1997.tb48147.x. Ann N Y Acad Sci. 1997. PMID: 9186722 Review. No abstract available.

4

Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity.

Rosenkilde MM, Benned-Jensen T, Andersen H, Holst PJ, Kledal TN, Lüttichau HR, Larsen JK, Christensen JP, Schwartz TW. Rosenkilde MM, et al. J Biol Chem. 2006 May 12;281(19):13199-13208. doi: 10.1074/jbc.M602245200. Epub 2006 Mar 15. J Biol Chem. 2006. PMID: 16540462 Free article.

5

Conformational constraining of inactive and active States of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V.

Rosenkilde MM, David R, Oerlecke I, Benned-Jensen T, Geumann U, Beck-Sickinger AG, Schwartz TW. Rosenkilde MM, et al. Mol Pharmacol. 2006 Dec;70(6):1892-901. doi: 10.1124/mol.106.027425. Epub 2006 Sep 13. Mol Pharmacol. 2006. PMID: 16971553

6

Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding.

Jensen PC, Thiele S, Ulven T, Schwartz TW, Rosenkilde MM. Jensen PC, et al. Among authors: rosenkilde mm. J Biol Chem. 2008 Aug 22;283(34):23121-8. doi: 10.1074/jbc.M803458200. Epub 2008 Jun 17. J Biol Chem. 2008. PMID: 18559339 Free article.

7

Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist.

Benned-Jensen T, Rosenkilde MM. Benned-Jensen T, et al. Among authors: rosenkilde mm. Mol Pharmacol. 2008 Oct;74(4):1008-21. doi: 10.1124/mol.108.049676. Epub 2008 Jul 15. Mol Pharmacol. 2008. PMID: 18628402

8

The role of transmembrane segment II in 7TM receptor activation.

Benned-Jensen T, Rosenkilde MM. Benned-Jensen T, et al. Among authors: rosenkilde mm. Curr Mol Pharmacol. 2009 Jun;2(2):140-8. doi: 10.2174/1874467210902020140. Curr Mol Pharmacol. 2009. PMID: 20021454

9

Distinct expression and ligand-binding profiles of two constitutively active GPR17 splice variants.

Benned-Jensen T, Rosenkilde MM. Benned-Jensen T, et al. Among authors: rosenkilde mm. Br J Pharmacol. 2010 Mar;159(5):1092-105. doi: 10.1111/j.1476-5381.2009.00633.x. Epub 2010 Feb 8. Br J Pharmacol. 2010. PMID: 20148890 Free PMC article.

10

The minor binding pocket: a major player in 7TM receptor activation.

Rosenkilde MM, Benned-Jensen T, Frimurer TM, Schwartz TW. Rosenkilde MM, et al. Trends Pharmacol Sci. 2010 Dec;31(12):567-74. doi: 10.1016/j.tips.2010.08.006. Epub 2010 Sep 25. Trends Pharmacol Sci. 2010. PMID: 20870300

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