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Page 1
Rational design of a highly immunogenic prefusion-stabilized F glycoprotein antigen for a respiratory syncytial virus vaccine.
Che Y, Gribenko AV, Song X, Handke LD, Efferen KS, Tompkins K, Kodali S, Nunez L, Prasad AK, Phelan LM, Ammirati M, Yu X, Lees JA, Chen W, Martinez L, Roopchand V, Han S, Qiu X, DeVincenzo JP, Jansen KU, Dormitzer PR, Swanson KA. Che Y, et al. Among authors: roopchand v. Sci Transl Med. 2023 Apr 26;15(693):eade6422. doi: 10.1126/scitranslmed.ade6422. Epub 2023 Apr 26. Sci Transl Med. 2023. PMID: 37023209
Non-propagating, recombinant vesicular stomatitis virus vectors encoding respiratory syncytial virus proteins generate potent humoral and cellular immunity against RSV and are protective in mice.
Johnson JE, McNeil LK, Megati S, Witko SE, Roopchand VS, Obregon JH, Illenberger DM, Kotash CS, Nowak RM, Braunstein E, Yurgelonis I, Jansen KU, Kalyan NK, Sidhu MK. Johnson JE, et al. Among authors: roopchand vs. Immunol Lett. 2013 Feb;150(1-2):134-44. doi: 10.1016/j.imlet.2012.12.005. Epub 2012 Dec 20. Immunol Lett. 2013. PMID: 23261719
Nonreplicating vaccines can protect african green monkeys from the memphis 37 strain of respiratory syncytial virus.
Eyles JE, Johnson JE, Megati S, Roopchand V, Cockle PJ, Weeratna R, Makinen S, Brown TP, Lang S, Witko SE, Kotash CS, Li J, West K, Maldonado O, Falconer DJ, Lees C, Smith GJ, White P, Wright P, Loudon PT, Merson JR, Jansen KU, Sidhu MK. Eyles JE, et al. Among authors: roopchand v. J Infect Dis. 2013 Jul 15;208(2):319-29. doi: 10.1093/infdis/jit169. Epub 2013 Apr 17. J Infect Dis. 2013. PMID: 23596321
Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques.
Luckay A, Sidhu MK, Kjeken R, Megati S, Chong SY, Roopchand V, Garcia-Hand D, Abdullah R, Braun R, Montefiori DC, Rosati M, Felber BK, Pavlakis GN, Mathiesen I, Israel ZR, Eldridge JH, Egan MA. Luckay A, et al. Among authors: roopchand v. J Virol. 2007 May;81(10):5257-69. doi: 10.1128/JVI.00055-07. Epub 2007 Feb 28. J Virol. 2007. PMID: 17329330 Free PMC article.
A dose sparing effect by plasmid encoded IL-12 adjuvant on a SIVgag-plasmid DNA vaccine in rhesus macaques.
Schadeck EB, Sidhu M, Egan MA, Chong SY, Piacente P, Masood A, Garcia-Hand D, Cappello S, Roopchand V, Megati S, Quiroz J, Boyer JD, Felber BK, Pavlakis GN, Weiner DB, Eldridge JH, Israel ZR. Schadeck EB, et al. Among authors: roopchand v. Vaccine. 2006 May 22;24(21):4677-87. doi: 10.1016/j.vaccine.2005.10.035. Epub 2005 Oct 26. Vaccine. 2006. PMID: 16288822
Modifying the HIV-1 env gp160 gene to improve pDNA vaccine-elicited cell-mediated immune responses.
Megati S, Garcia-Hand D, Cappello S, Roopchand V, Masood A, Xu R, Luckay A, Chong SY, Rosati M, Sackitey S, Weiner DB, Felber BK, Pavlakis GN, Israel ZR, Smith LR, Eldridge JH, Sidhu MK, Egan MA. Megati S, et al. Among authors: roopchand v. Vaccine. 2008 Sep 19;26(40):5083-94. doi: 10.1016/j.vaccine.2008.03.092. Epub 2008 Apr 24. Vaccine. 2008. PMID: 18485543 Free PMC article.
Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.
Kutzler MA, Robinson TM, Chattergoon MA, Choo DK, Choo AY, Choe PY, Ramanathan MP, Parkinson R, Kudchodkar S, Tamura Y, Sidhu M, Roopchand V, Kim JJ, Pavlakis GN, Felber BK, Waldmann TA, Boyer JD, Weiner DB. Kutzler MA, et al. Among authors: roopchand v. J Immunol. 2005 Jul 1;175(1):112-23. doi: 10.4049/jimmunol.175.1.112. J Immunol. 2005. PMID: 15972637