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A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis.
Durán-Sotuela A, Fernandez-Moreno M, Suárez-Ulloa V, Vázquez-García J, Relaño S, Hermida-Gómez T, Balboa-Barreiro V, Lourido-Salas L, Calamia V, Fernandez-Puente P, Ruiz-Romero C, Fernández-Tajes J, Vaamonde-García C, de Andrés MC, Oreiro N, Blanco FJ, Rego-Perez I. Durán-Sotuela A, et al. Ann Rheum Dis. 2023 Jul;82(7):974-984. doi: 10.1136/ard-2022-223570. Epub 2023 Apr 6. Ann Rheum Dis. 2023. PMID: 37024296 Free PMC article.
Single nucleotide polymorphism genes and mitochondrial DNA haplogroups as biomarkers for early prediction of knee osteoarthritis structural progressors: use of supervised machine learning classifiers.
Bonakdari H, Pelletier JP, Blanco FJ, Rego-Pérez I, Durán-Sotuela A, Aitken D, Jones G, Cicuttini F, Jamshidi A, Abram F, Martel-Pelletier J. Bonakdari H, et al. Among authors: duran sotuela a. BMC Med. 2022 Sep 12;20(1):316. doi: 10.1186/s12916-022-02491-1. BMC Med. 2022. PMID: 36089590 Free PMC article.
mtDNA haplogroup A enhances the effect of obesity on the risk of knee OA in a Mexican population.
Ramos-Louro P, Arellano Pérez Vertti RD, Reyes AL, Martínez-Nava GA, Espinosa R, Pineda C, González Galarza FF, Argüello Astorga R, Aguilar Muñiz LS, Hernández Terán F, Parra Torres NM, Durán Sotuela A, Fernández-Moreno M, Balboa Barreiro V, Blanco FJ, Rego-Pérez I. Ramos-Louro P, et al. Among authors: duran sotuela a. Sci Rep. 2022 Mar 25;12(1):5173. doi: 10.1038/s41598-022-09265-y. Sci Rep. 2022. PMID: 35338224 Free PMC article.
Genetic biomarkers in osteoarthritis: a quick overview.
Rego-Pérez I, Durán-Sotuela A, Ramos-Louro P, Blanco FJ. Rego-Pérez I, et al. Among authors: duran sotuela a. Fac Rev. 2021 Nov 10;10:78. doi: 10.12703/r/10-78. eCollection 2021. Fac Rev. 2021. PMID: 35028644 Free PMC article. Review.
Oleate Prevents Palmitate-Induced Mitochondrial Dysfunction in Chondrocytes.
Vázquez-Mosquera ME, Fernández-Moreno M, Cortés-Pereira E, Relaño S, Dalmao-Fernández A, Ramos-Louro P, Durán Sotuela A, Rego-Pérez I, Blanco FJ. Vázquez-Mosquera ME, et al. Among authors: duran sotuela a. Front Physiol. 2021 Jun 15;12:670753. doi: 10.3389/fphys.2021.670753. eCollection 2021. Front Physiol. 2021. PMID: 34211401 Free PMC article.
Mitochondrial Genetics and Epigenetics in Osteoarthritis.
Rego-Pérez I, Durán-Sotuela A, Ramos-Louro P, Blanco FJ. Rego-Pérez I, et al. Among authors: duran sotuela a. Front Genet. 2020 Jan 17;10:1335. doi: 10.3389/fgene.2019.01335. eCollection 2019. Front Genet. 2020. PMID: 32010192 Free PMC article. Review.
Differential Association of Mitochondrial DNA Haplogroups J and H With the Methylation Status of Articular Cartilage: Potential Role in Apoptosis and Metabolic and Developmental Processes.
Cortés-Pereira E, Fernández-Tajes J, Fernández-Moreno M, Vázquez-Mosquera ME, Relaño S, Ramos-Louro P, Durán-Sotuela A, Dalmao-Fernández A, Oreiro N, Blanco FJ, Rego-Pérez I. Cortés-Pereira E, et al. Among authors: duran sotuela a. Arthritis Rheumatol. 2019 Jul;71(7):1191-1200. doi: 10.1002/art.40857. Epub 2019 May 21. Arthritis Rheumatol. 2019. PMID: 30747498