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Page 1
Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease.
Vicente-Rodríguez M, Mancuso R, Peris-Yague A, Simmons C; NIMA Consortium; Gómez-Nicola D, Perry VH, Turkheimer F, Lovestone S, Parker CA, Cash D. Vicente-Rodríguez M, et al. Among authors: lovestone s. J Neuroinflammation. 2023 Apr 9;20(1):92. doi: 10.1186/s12974-023-02769-y. J Neuroinflammation. 2023. PMID: 37032328 Free PMC article.
Glycosylated clusterin species facilitate Aβ toxicity in human neurons.
Foster EM, Fernandes M, Dangla-Valls A, Hublitz P, Pangalos M, Lovestone S, Ribe EM, Buckley NJ. Foster EM, et al. Among authors: lovestone s. Sci Rep. 2022 Nov 3;12(1):18639. doi: 10.1038/s41598-022-23167-z. Sci Rep. 2022. PMID: 36329114 Free PMC article.
Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability.
Ng B, Rowland HA, Wei T, Arunasalam K, Hayes EM, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Ffytche D, Gunn RN, Kocagoncu E, Lawson J, Malhotra PA, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Buckley NJ, Cader ZM, Lovestone S, Wade-Martins R. Ng B, et al. Among authors: lovestone s. Brain Commun. 2022 Oct 21;4(6):fcac267. doi: 10.1093/braincomms/fcac267. eCollection 2022. Brain Commun. 2022. PMID: 36349119 Free PMC article.
Identification of a possible proteomic biomarker in Parkinson's disease: discovery and replication in blood, brain and cerebrospinal fluid.
Winchester L, Barber I, Lawton M, Ash J, Liu B, Evetts S, Hopkins-Jones L, Lewis S, Bresner C, Malpartida AB, Williams N, Gentlemen S, Wade-Martins R, Ryan B, Holgado-Nevado A, Hu M, Ben-Shlomo Y, Grosset D, Lovestone S. Winchester L, et al. Among authors: lovestone s. Brain Commun. 2022 Dec 28;5(1):fcac343. doi: 10.1093/braincomms/fcac343. eCollection 2023. Brain Commun. 2022. PMID: 36694577 Free PMC article.
Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease.
Gómez-Pascual A, Naccache T, Xu J, Hooshmand K, Wretlind A, Gabrielli M, Lombardo MT, Shi L, Buckley NJ, Tijms BM, Vos SJB, Ten Kate M, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, Popp J, Martinez-Lage P, Streffer J, Barkhof F, Zetterberg H, Visser PJ, Lovestone S, Bertram L, Nevado-Holgado AJ, Gualerzi A, Picciolini S, Proitsi P, Verderio C, Botía JA, Legido-Quigley C. Gómez-Pascual A, et al. Among authors: lovestone s. Comput Biol Med. 2024 May 13;176:108588. doi: 10.1016/j.compbiomed.2024.108588. Online ahead of print. Comput Biol Med. 2024. PMID: 38761503 Free article.
Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants.
He KY, Khramtsova EA, Cabrera-Socorro A, Zhang Y, Li S, Sarver BAJ, Smets B, Li QS, De Muynck L, Parrado AR, Lovestone S, Black MH. He KY, et al. Among authors: lovestone s. Mol Neurodegener. 2023 Nov 28;18(1):92. doi: 10.1186/s13024-023-00684-7. Mol Neurodegener. 2023. PMID: 38017580 Free PMC article. No abstract available.
Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning.
Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, Blin O, Richardson JC, Bordet R, Lleó A, Alcolea D, Popp J, Marsh TW, Gorijala P, Clark C, Peyratout G, Martinez-Lage P, Tainta M, Dobson RJB, Legido-Quigley C, Van Broeckhoven C, Tanzi RE, Ten Kate M, Lill CM, Barkhof F, Cruchaga C, Lovestone S, Streffer J, Zetterberg H, Visser PJ, Sleegers K, Bertram L; EMIF-AD & ADNI study group. Neumann A, et al. Among authors: lovestone s. Genome Med. 2023 Oct 4;15(1):79. doi: 10.1186/s13073-023-01233-z. Genome Med. 2023. PMID: 37794492 Free PMC article.
Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease.
Shi L, Xu J, Green R, Wretlind A, Homann J, Buckley NJ, Tijms BM, Vos SJB, Lill CM, Kate MT, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, Popp J, Martinez-Lage P, Streffer J, Barkhof F, Zetterberg H, Visser PJ, Lovestone S, Bertram L, Nevado-Holgado AJ, Proitsi P, Legido-Quigley C. Shi L, et al. Among authors: lovestone s. Alzheimers Dement. 2023 Aug;19(8):3350-3364. doi: 10.1002/alz.12961. Epub 2023 Feb 15. Alzheimers Dement. 2023. PMID: 36790009
Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks.
Zhang Y, Ghose U, Buckley NJ, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, Popp J, Martinez-Lage P, Legido-Quigley C, Barkhof F, Zetterberg H, Visser PJ, Bertram L, Lovestone S, Nevado-Holgado AJ, Shi L. Zhang Y, et al. Among authors: lovestone s. Front Aging Neurosci. 2022 Nov 29;14:1040001. doi: 10.3389/fnagi.2022.1040001. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36523958 Free PMC article.
482 results