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Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease.
Front Genet. 2023 Mar 24;14:1118649. doi: 10.3389/fgene.2023.1118649. eCollection 2023.
Front Genet. 2023.
PMID: 37035740
Free PMC article.
Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease.
Cain JT, Likhite S, White KA, Timm DJ, Davis SS, Johnson TB, Dennys-Rivers CN, Rinaldi F, Motti D, Corcoran S, Morales P, Pierson C, Hughes SM, Lee SY, Kaspar BK, Meyer K, Weimer JM.
Cain JT, et al. Among authors: dennys rivers cn.
Mol Ther. 2019 Oct 2;27(10):1836-1847. doi: 10.1016/j.ymthe.2019.06.015. Epub 2019 Jul 10.
Mol Ther. 2019.
PMID: 31331814
Free PMC article.
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Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis.
Strayer AL, Dennys-Rivers CN, Ricart KC, Bae N, Beckman JS, Franco MC, Estevez AG.
Strayer AL, et al. Among authors: dennys rivers cn.
Exp Biol Med (Maywood). 2019 Aug;244(11):901-914. doi: 10.1177/1535370219853798. Epub 2019 May 29.
Exp Biol Med (Maywood). 2019.
PMID: 31142143
Free PMC article.
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