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PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion.
Jensen CC, Clements AN, Liou H, Ball LE, Bethard JR, Langlais PR, Toth RK, Chauhan SS, Casillas AL, Daulat SR, Kraft AS, Cress AE, Miranti CK, Mouneimne G, Rogers GC, Warfel NA. Jensen CC, et al. Among authors: warfel na. J Cell Biol. 2023 Jun 5;222(6):e202208136. doi: 10.1083/jcb.202208136. Epub 2023 Apr 12. J Cell Biol. 2023. PMID: 37042842 Free PMC article.
PIM kinase (and Akt) biology and signaling in tumors.
Warfel NA, Kraft AS. Warfel NA, et al. Pharmacol Ther. 2015 Jul;151:41-9. doi: 10.1016/j.pharmthera.2015.03.001. Epub 2015 Mar 5. Pharmacol Ther. 2015. PMID: 25749412 Free PMC article. Review.
Insulin receptor substrate 1 is a substrate of the Pim protein kinases.
Song JH, Padi SK, Luevano LA, Minden MD, DeAngelo DJ, Hardiman G, Ball LE, Warfel NA, Kraft AS. Song JH, et al. Among authors: warfel na. Oncotarget. 2016 Apr 12;7(15):20152-65. doi: 10.18632/oncotarget.7918. Oncotarget. 2016. PMID: 26956053 Free PMC article.
Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase.
Song JH, Singh N, Luevano LA, Padi SKR, Okumura K, Olive V, Black SM, Warfel NA, Goodrich DW, Kraft AS. Song JH, et al. Among authors: warfel na. Mol Cancer Ther. 2018 Dec;17(12):2710-2721. doi: 10.1158/1535-7163.MCT-18-0374. Epub 2018 Sep 6. Mol Cancer Ther. 2018. PMID: 30190422 Free PMC article.
Gene Editing of α6 Integrin Inhibits Muscle Invasive Networks and Increases Cell-Cell Biophysical Properties in Prostate Cancer.
Rubenstein CS, Gard JMC, Wang M, McGrath JE, Ingabire N, Hinton JP, Marr KD, Simpson SJ, Nagle RB, Miranti CK, Warfel NA, Garcia JGN, Arif-Tiwari H, Cress AE. Rubenstein CS, et al. Among authors: warfel na. Cancer Res. 2019 Sep 15;79(18):4703-4714. doi: 10.1158/0008-5472.CAN-19-0868. Epub 2019 Jul 23. Cancer Res. 2019. PMID: 31337652 Free PMC article.
37 results