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The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining.
Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcalá K, Ball K, Proctor B 3rd, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. Fleury H, et al. Among authors: sempeck c. Mol Cell. 2023 May 4;83(9):1429-1445.e8. doi: 10.1016/j.molcel.2023.03.017. Epub 2023 Apr 11. Mol Cell. 2023. PMID: 37044098 Free PMC article.
Androgen Receptor Regulates CD44 Expression in Bladder Cancer.
Sottnik JL, Vanderlinden L, Joshi M, Chauca-Diaz A, Owens C, Hansel DE, Sempeck C, Ghosh D, Theodorescu D. Sottnik JL, et al. Among authors: sempeck c. Cancer Res. 2021 Jun 1;81(11):2833-2846. doi: 10.1158/0008-5472.CAN-20-3095. Epub 2021 Mar 9. Cancer Res. 2021. PMID: 33687952 Free PMC article.
JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.
Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, Smith K, Granrath R, Tracy D, Baxter J, Espinosa JM, Sullivan KD. Tuttle KD, et al. Among authors: sempeck c. Cell Rep. 2020 Nov 17;33(7):108407. doi: 10.1016/j.celrep.2020.108407. Cell Rep. 2020. PMID: 33207208 Free PMC article.