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Stricturing Crohn's Disease Single-Cell RNA Sequencing Reveals Fibroblast Heterogeneity and Intercellular Interactions.
Mukherjee PK, Nguyen QT, Li J, Zhao S, Christensen SM, West GA, Chandra J, Gordon IO, Lin S, Wang J, Mao R, Czarnecki D, Rayan C, Goren I, Banerjee S, Kotak P, Plesec T, Lal S, Fabre T, Asano S, Bound K, Hart K, Park C, Martinez R, Dower K, Wynn TA, Hu S, Naydenov N, Decaris M, Turner S, Holubar SD, Steele SR, Fiocchi C, Ivanov AI, Kravarik KM, Rieder F. Mukherjee PK, et al. Among authors: wynn ta. Gastroenterology. 2023 Nov;165(5):1180-1196. doi: 10.1053/j.gastro.2023.07.014. Epub 2023 Jul 26. Gastroenterology. 2023. PMID: 37507073
Stricturing Crohn's disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactions.
Mukherjee PK, Nguyen QT, Li J, Zhao S, Christensen SM, West GA, Chandra J, Gordon IO, Lin S, Wang J, Mao R, Czarnecki D, Rayan C, Kotak P, Plesec T, Lal S, Fabre T, Asano S, Bound K, Hart K, Park C, Martinez R, Dower K, Wynn TA, Hu S, Naydenov N, Decaris M, Turner S, Holubar SD, Steele SR, Fiocchi C, Ivanov AI, Kravarik KM, Rieder F. Mukherjee PK, et al. Among authors: wynn ta. bioRxiv [Preprint]. 2023 Apr 4:2023.04.03.534781. doi: 10.1101/2023.04.03.534781. bioRxiv. 2023. PMID: 37066202 Free PMC article. Updated. Preprint.
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation.
Fabre T, Barron AMS, Christensen SM, Asano S, Bound K, Lech MP, Wadsworth MH 2nd, Chen X, Wang C, Wang J, McMahon J, Schlerman F, White A, Kravarik KM, Fisher AJ, Borthwick LA, Hart KM, Henderson NC, Wynn TA, Dower K. Fabre T, et al. Among authors: wynn ta. Sci Immunol. 2023 Apr 14;8(82):eadd8945. doi: 10.1126/sciimmunol.add8945. Epub 2023 Apr 7. Sci Immunol. 2023. PMID: 37027478
Epithelial-intrinsic defects in TGFβR signaling drive local allergic inflammation manifesting as eosinophilic esophagitis.
Laky K, Kinard JL, Li JM, Moore IN, Lack J, Fischer ER, Kabat J, Latanich R, Zachos NC, Limkar AR, Weissler KA, Thompson RW, Wynn TA, Dietz HC, Guerrerio AL, Frischmeyer-Guerrerio PA. Laky K, et al. Among authors: wynn ta. Sci Immunol. 2023 Jan 6;8(79):eabp9940. doi: 10.1126/sciimmunol.abp9940. Epub 2023 Jan 6. Sci Immunol. 2023. PMID: 36608150 Free PMC article.
Enhanced oxygen evolution over dual corner-shared cobalt tetrahedra.
Chen Y, Seo JK, Sun Y, Wynn TA, Olguin M, Zhang M, Wang J, Xi S, Du Y, Yuan K, Chen W, Fisher AC, Wang M, Feng Z, Gracia J, Huang L, Du S, Gao HJ, Meng YS, Xu ZJ. Chen Y, et al. Among authors: wynn ta. Nat Commun. 2022 Sep 20;13(1):5510. doi: 10.1038/s41467-022-33000-w. Nat Commun. 2022. PMID: 36127321 Free PMC article.
Single-cell analyses of Crohn's disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions.
Jaeger N, Gamini R, Cella M, Schettini JL, Bugatti M, Zhao S, Rosadini CV, Esaulova E, Di Luccia B, Kinnett B, Vermi W, Artyomov MN, Wynn TA, Xavier RJ, Jelinsky SA, Colonna M. Jaeger N, et al. Among authors: wynn ta. Nat Commun. 2021 Mar 26;12(1):1921. doi: 10.1038/s41467-021-22164-6. Nat Commun. 2021. PMID: 33771991 Free PMC article.
Fibrosis: from mechanisms to medicines.
Henderson NC, Rieder F, Wynn TA. Henderson NC, et al. Among authors: wynn ta. Nature. 2020 Nov;587(7835):555-566. doi: 10.1038/s41586-020-2938-9. Epub 2020 Nov 25. Nature. 2020. PMID: 33239795 Free PMC article. Review.
Opinion on Immune Tolerance Therapeutic Development.
Radi ZA, Wynn TA. Radi ZA, et al. Among authors: wynn ta. Toxicol Pathol. 2020 Aug;48(6):712-717. doi: 10.1177/0192623320948805. Epub 2020 Aug 20. Toxicol Pathol. 2020. PMID: 32815472 Review.
243 results