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Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling.
Mol Cell. 2023 May 18;83(10):1743-1760.e11. doi: 10.1016/j.molcel.2023.03.027. Epub 2023 Apr 27.
Mol Cell. 2023.
PMID: 37116497
Free PMC article.
The recruitment of ACF1 and SMARCA5 to DNA lesions relies on ADP-ribosylation dependent chromatin unfolding.
Pinto Jurado E, Smith R, Bigot N, Chapuis C, Timinszky G, Huet S.
Pinto Jurado E, et al.
Mol Biol Cell. 2024 Mar 1;35(3):br7. doi: 10.1091/mbc.E23-07-0281. Epub 2024 Jan 3.
Mol Biol Cell. 2024.
PMID: 38170578
Free PMC article.
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The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity.
Mamar H, Fajka-Boja R, Mórocz M, Jurado EP, Zentout S, Mihuţ A, Kopasz AG, Mérey M, Smith R, Sharma AB, Lakin ND, Bowman AJ, Haracska L, Huet S, Timinszky G.
Mamar H, et al. Among authors: jurado ep.
Nucleic Acids Res. 2024 Jun 3:gkae439. doi: 10.1093/nar/gkae439. Online ahead of print.
Nucleic Acids Res. 2024.
PMID: 38828775
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