Schuller M - Search Results

1

Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling.

Longarini EJ, Dauben H, Locatelli C, Wondisford AR, Smith R, Muench C, Kolvenbach A, Lynskey ML, Pope A, Bonfiglio JJ, Jurado EP, Fajka-Boja R, Colby T, Schuller M, Ahel I, Timinszky G, O'Sullivan RJ, Huet S, Matic I. Longarini EJ, et al. Among authors: schuller m. Mol Cell. 2023 May 18;83(10):1743-1760.e11. doi: 10.1016/j.molcel.2023.03.027. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116497 Free PMC article.

2

Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.

Moustakim M, Riedel K, Schuller M, Gehring AP, Monteiro OP, Martin SP, Fedorov O, Heer J, Dixon DJ, Elkins JM, Knapp S, Bracher F, Brennan PE. Moustakim M, et al. Among authors: schuller m. Bioorg Med Chem. 2018 Jul 15;26(11):2965-2972. doi: 10.1016/j.bmc.2018.03.020. Epub 2018 Mar 12. Bioorg Med Chem. 2018. PMID: 29567296 Free PMC article.

3

Simultaneous Multiple MS Binding Assays Addressing D₁ and D₂ Dopamine Receptors.

Schuller M, Höfner G, Wanner KT. Schuller M, et al. ChemMedChem. 2017 Oct 9;12(19):1585-1594. doi: 10.1002/cmdc.201700369. Epub 2017 Sep 1. ChemMedChem. 2017. PMID: 28776962

4

Corrigendum: Simultaneous Multiple MS Binding Assays Addressing D₁ and D₂ Dopamine Receptors.

Schuller M, Höfner G, Wanner KT. Schuller M, et al. ChemMedChem. 2017 Oct 20;12(20):1737. doi: 10.1002/cmdc.201700588. Epub 2017 Oct 4. ChemMedChem. 2017. PMID: 29052366 No abstract available.

5

Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential.

Rack JGM, Zorzini V, Zhu Z, Schuller M, Ahel D, Ahel I. Rack JGM, et al. Among authors: schuller m. Open Biol. 2020 Nov;10(11):200237. doi: 10.1098/rsob.200237. Epub 2020 Nov 18. Open Biol. 2020. PMID: 33202171 Free PMC article.

6

Molecular basis for DarT ADP-ribosylation of a DNA base.

Schuller M, Butler RE, Ariza A, Tromans-Coia C, Jankevicius G, Claridge TDW, Kendall SL, Goh S, Stewart GR, Ahel I. Schuller M, et al. Nature. 2021 Aug;596(7873):597-602. doi: 10.1038/s41586-021-03825-4. Epub 2021 Aug 18. Nature. 2021. PMID: 34408320

7

Beyond protein modification: the rise of non-canonical ADP-ribosylation.

Schuller M, Ahel I. Schuller M, et al. Biochem J. 2022 Feb 17;479(4):463-477. doi: 10.1042/BCJ20210280. Biochem J. 2022. PMID: 35175282 Free PMC article.

8

Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA.

Hloušek-Kasun A, Mikolčević P, Rack JGM, Tromans-Coia C, Schuller M, Jankevicius G, Matković M, Bertoša B, Ahel I, Mikoč A. Hloušek-Kasun A, et al. Among authors: schuller m. Comput Struct Biotechnol J. 2022 Aug 8;20:4337-4350. doi: 10.1016/j.csbj.2022.08.002. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 36051881 Free PMC article.

9

Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors.

Schuller M, Zarganes-Tzitzikas T, Bennett J, De Cesco S, Fearon D, von Delft F, Fedorov O, Brennan PE, Ahel I. Schuller M, et al. Pathogens. 2023 Feb 15;12(2):324. doi: 10.3390/pathogens12020324. Pathogens. 2023. PMID: 36839595 Free PMC article.

10

Updated protein domain annotation of the PARP protein family sheds new light on biological function.

Suskiewicz MJ, Munnur D, Strømland Ø, Yang JC, Easton LE, Chatrin C, Zhu K, Baretić D, Goffinont S, Schuller M, Wu WF, Elkins JM, Ahel D, Sanyal S, Neuhaus D, Ahel I. Suskiewicz MJ, et al. Among authors: schuller m. Nucleic Acids Res. 2023 Aug 25;51(15):8217-8236. doi: 10.1093/nar/gkad514. Nucleic Acids Res. 2023. PMID: 37326024 Free PMC article.

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