Tolbert WD - Search Results

1

Structure-function Analyses Reveal Key Molecular Determinants of HIV-1 CRF01_AE Resistance to the Entry Inhibitor Temsavir.

Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. Among authors: tolbert wd. bioRxiv [Preprint]. 2023 Apr 17:2023.04.17.537181. doi: 10.1101/2023.04.17.537181. bioRxiv. 2023. PMID: 37131729 Free PMC article. Updated. Preprint.

2

Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant.

Tolbert WD, Zhang Y, Cottet SE, Bennett EM, Ekstrom JL, Pegg AE, Ealick SE. Tolbert WD, et al. Biochemistry. 2003 Mar 4;42(8):2386-95. doi: 10.1021/bi0268854. Biochemistry. 2003. PMID: 12600205

3

A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist.

Tolbert WD, Daugherty J, Gao C, Xie Q, Miranti C, Gherardi E, Vande Woude G, Xu HE. Tolbert WD, et al. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14592-7. doi: 10.1073/pnas.0704290104. Epub 2007 Sep 5. Proc Natl Acad Sci U S A. 2007. PMID: 17804794 Free PMC article.

4

The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase.

Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE. Tolbert WD, et al. Biochemistry. 2001 Aug 14;40(32):9484-94. doi: 10.1021/bi010735w. Biochemistry. 2001. PMID: 11583147

5

Doubling the size of the glucocorticoid receptor ligand binding pocket by deacylcortivazol.

Suino-Powell K, Xu Y, Zhang C, Tao YG, Tolbert WD, Simons SS Jr, Xu HE. Suino-Powell K, et al. Among authors: tolbert wd. Mol Cell Biol. 2008 Mar;28(6):1915-23. doi: 10.1128/MCB.01541-07. Epub 2007 Dec 26. Mol Cell Biol. 2008. PMID: 18160712 Free PMC article.

6

Structure of a human S-adenosylmethionine decarboxylase self-processing ester intermediate and mechanism of putrescine stimulation of processing as revealed by the H243A mutant.

Ekstrom JL, Tolbert WD, Xiong H, Pegg AE, Ealick SE. Ekstrom JL, et al. Among authors: tolbert wd. Biochemistry. 2001 Aug 14;40(32):9495-504. doi: 10.1021/bi010736o. Biochemistry. 2001. PMID: 11583148

7

3-Deoxy-D-manno-octulosonate-8-phosphate synthase from Escherichia coli. Model of binding of phosphoenolpyruvate and D-arabinose-5-phosphate.

Wagner T, Kretsinger RH, Bauerle R, Tolbert WD. Wagner T, et al. Among authors: tolbert wd. J Mol Biol. 2000 Aug 11;301(2):233-8. doi: 10.1006/jmbi.2000.3956. J Mol Biol. 2000. PMID: 10926505

8

Structure of neurolysin reveals a deep channel that limits substrate access.

Brown CK, Madauss K, Lian W, Beck MR, Tolbert WD, Rodgers DW. Brown CK, et al. Among authors: tolbert wd. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3127-32. doi: 10.1073/pnas.051633198. Epub 2001 Mar 6. Proc Natl Acad Sci U S A. 2001. PMID: 11248043 Free PMC article.

9

Structural basis for agonism and antagonism of hepatocyte growth factor.

Tolbert WD, Daugherty-Holtrop J, Gherardi E, Vande Woude G, Xu HE. Tolbert WD, et al. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13264-9. doi: 10.1073/pnas.1005183107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624990 Free PMC article.

10

Crystallization and preliminary crystallographic studies of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Escherichia coli.

Tolbert WD, Moll JR, Bauerle R, Kretsinger RH. Tolbert WD, et al. Proteins. 1996 Mar;24(3):407-8. doi: 10.1002/(SICI)1097-0134(199603)24:3<407::AID-PROT16>3.0.CO;2-Q. Proteins. 1996. PMID: 8778790

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