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Molecular insights into peptide agonist engagement with the PTH receptor.
Structure. 2023 Jun 1;31(6):668-676.e5. doi: 10.1016/j.str.2023.04.002. Epub 2023 May 5.
Structure. 2023.
PMID: 37148874
New Insights into the Structure and Function of Class B1 GPCRs.
Cary BP, Zhang X, Cao J, Johnson RM, Piper SJ, Gerrard EJ, Wootten D, Sexton PM.
Cary BP, et al. Among authors: gerrard ej.
Endocr Rev. 2023 May 8;44(3):492-517. doi: 10.1210/endrev/bnac033.
Endocr Rev. 2023.
PMID: 36546772
Free PMC article.
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Structural insight into selectivity of amylin and calcitonin receptor agonists.
Cao J, Belousoff MJ, Gerrard E, Danev R, Fletcher MM, Dal Maso E, Schreuder H, Lorenz K, Evers A, Tiwari G, Besenius M, Li Z, Johnson RM, Wootten D, Sexton PM.
Cao J, et al.
Nat Chem Biol. 2024 Feb;20(2):162-169. doi: 10.1038/s41589-023-01393-4. Epub 2023 Aug 3.
Nat Chem Biol. 2024.
PMID: 37537379
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Structure-guided optimization of light-activated chimeric G-protein-coupled receptors.
Tichy AM, So WL, Gerrard EJ, Janovjak H.
Tichy AM, et al. Among authors: gerrard ej.
Structure. 2022 Aug 4;30(8):1075-1087.e4. doi: 10.1016/j.str.2022.04.012. Epub 2022 May 18.
Structure. 2022.
PMID: 35588733
Free article.
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Light-activated chimeric GPCRs: limitations and opportunities.
Tichy AM, Gerrard EJ, Sexton PM, Janovjak H.
Tichy AM, et al. Among authors: gerrard ej.
Curr Opin Struct Biol. 2019 Aug;57:196-203. doi: 10.1016/j.sbi.2019.05.006. Epub 2019 Jun 14.
Curr Opin Struct Biol. 2019.
PMID: 31207383
Review.
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Engineering Strategy and Vector Library for the Rapid Generation of Modular Light-Controlled Protein-Protein Interactions.
Tichy AM, Gerrard EJ, Legrand JMD, Hobbs RM, Janovjak H.
Tichy AM, et al. Among authors: gerrard ej.
J Mol Biol. 2019 Aug 9;431(17):3046-3055. doi: 10.1016/j.jmb.2019.05.033. Epub 2019 May 29.
J Mol Biol. 2019.
PMID: 31150735
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Optical functionalization of human Class A orphan G-protein-coupled receptors.
Morri M, Sanchez-Romero I, Tichy AM, Kainrath S, Gerrard EJ, Hirschfeld PP, Schwarz J, Janovjak H.
Morri M, et al. Among authors: gerrard ej.
Nat Commun. 2018 May 16;9(1):1950. doi: 10.1038/s41467-018-04342-1.
Nat Commun. 2018.
PMID: 29769519
Free PMC article.
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Optogenetic interrogation reveals separable G-protein-dependent and -independent signalling linking G-protein-coupled receptors to the circadian oscillator.
Bailes HJ, Milosavljevic N, Zhuang LY, Gerrard EJ, Nishiguchi T, Ozawa T, Lucas RJ.
Bailes HJ, et al. Among authors: gerrard ej.
BMC Biol. 2017 May 15;15(1):40. doi: 10.1186/s12915-017-0380-8.
BMC Biol. 2017.
PMID: 28506231
Free PMC article.
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