Piper SJ - Search Results

1

Impact of secretin receptor homo-dimerization on natural ligand binding.

Harikumar KG, Piper SJ, Christopoulos A, Wootten D, Sexton PM, Miller LJ. Harikumar KG, et al. Among authors: piper sj. Nat Commun. 2024 May 23;15(1):4390. doi: 10.1038/s41467-024-48853-6. Nat Commun. 2024. PMID: 38782989 Free PMC article.

2

Molecular insights into peptide agonist engagement with the PTH receptor.

Cary BP, Gerrard EJ, Belousoff MJ, Fletcher MM, Jiang Y, Russell IC, Piper SJ, Wootten D, Sexton PM. Cary BP, et al. Among authors: piper sj. Structure. 2023 Jun 1;31(6):668-676.e5. doi: 10.1016/j.str.2023.04.002. Epub 2023 May 5. Structure. 2023. PMID: 37148874

3

New Insights into the Structure and Function of Class B1 GPCRs.

Cary BP, Zhang X, Cao J, Johnson RM, Piper SJ, Gerrard EJ, Wootten D, Sexton PM. Cary BP, et al. Among authors: piper sj. Endocr Rev. 2023 May 8;44(3):492-517. doi: 10.1210/endrev/bnac033. Endocr Rev. 2023. PMID: 36546772 Free PMC article.

4

Understanding VPAC receptor family peptide binding and selectivity.

Piper SJ, Deganutti G, Lu J, Zhao P, Liang YL, Lu Y, Fletcher MM, Hossain MA, Christopoulos A, Reynolds CA, Danev R, Sexton PM, Wootten D. Piper SJ, et al. Nat Commun. 2022 Nov 16;13(1):7013. doi: 10.1038/s41467-022-34629-3. Nat Commun. 2022. PMID: 36385145 Free PMC article.

5

Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors.

Lu J, Piper SJ, Zhao P, Miller LJ, Wootten D, Sexton PM. Lu J, et al. Among authors: piper sj. Int J Mol Sci. 2022 Jul 22;23(15):8069. doi: 10.3390/ijms23158069. Int J Mol Sci. 2022. PMID: 35897648 Free PMC article. Review.

6

Membranes under the Magnetic Lens: A Dive into the Diverse World of Membrane Protein Structures Using Cryo-EM.

Piper SJ, Johnson RM, Wootten D, Sexton PM. Piper SJ, et al. Chem Rev. 2022 Sep 14;122(17):13989-14017. doi: 10.1021/acs.chemrev.1c00837. Epub 2022 Jul 18. Chem Rev. 2022. PMID: 35849490 Free PMC article. Review.

7

A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid.

Perlaza-Jiménez L, Tan KS, Piper SJ, Johnson RM, Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T, Belousoff MJ. Perlaza-Jiménez L, et al. Among authors: piper sj. Microbiol Spectr. 2022 Aug 31;10(4):e0058322. doi: 10.1128/spectrum.00583-22. Epub 2022 Jun 23. Microbiol Spectr. 2022. PMID: 35736238 Free PMC article.

8

Secretin Amino-Terminal Structure-Activity Relationships and Complementary Mutagenesis at the Site of Docking to the Secretin Receptor.

Milburn JE, Harikumar KG, Piper SJ, Raval S, Christopoulos A, Wootten D, Sexton PM, Miller LJ. Milburn JE, et al. Among authors: piper sj. Mol Pharmacol. 2022 Jun;101(6):400-407. doi: 10.1124/molpharm.122.000502. Epub 2022 Mar 29. Mol Pharmacol. 2022. PMID: 35351821 Free PMC article.

9

Structural and functional diversity among agonist-bound states of the GLP-1 receptor.

Cary BP, Deganutti G, Zhao P, Truong TT, Piper SJ, Liu X, Belousoff MJ, Danev R, Sexton PM, Wootten D, Gellman SH. Cary BP, et al. Among authors: piper sj. Nat Chem Biol. 2022 Mar;18(3):256-263. doi: 10.1038/s41589-021-00945-w. Epub 2021 Dec 22. Nat Chem Biol. 2022. PMID: 34937906 Free PMC article.

10

Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor.

Johnson RM, Zhang X, Piper SJ, Nettleton TJ, Vandekolk TH, Langmead CJ, Danev R, Sexton PM, Wootten D. Johnson RM, et al. Among authors: piper sj. Biochem Biophys Res Commun. 2021 Nov 12;578:84-90. doi: 10.1016/j.bbrc.2021.09.016. Epub 2021 Sep 16. Biochem Biophys Res Commun. 2021. PMID: 34547628

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