Wootten D - Search Results

1

Molecular insights into peptide agonist engagement with the PTH receptor.

Cary BP, Gerrard EJ, Belousoff MJ, Fletcher MM, Jiang Y, Russell IC, Piper SJ, Wootten D, Sexton PM. Cary BP, et al. Among authors: wootten d. Structure. 2023 Jun 1;31(6):668-676.e5. doi: 10.1016/j.str.2023.04.002. Epub 2023 May 5. Structure. 2023. PMID: 37148874

2

Receptor activity modifying proteins (RAMPs) interact with the VPAC2 receptor and CRF1 receptors and modulate their function.

Wootten D, Lindmark H, Kadmiel M, Willcockson H, Caron KM, Barwell J, Drmota T, Poyner DR. Wootten D, et al. Br J Pharmacol. 2013 Feb;168(4):822-34. doi: 10.1111/j.1476-5381.2012.02202.x. Br J Pharmacol. 2013. PMID: 22946657 Free PMC article.

3

Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors.

Wheatley M, Simms J, Hawtin SR, Wesley VJ, Wootten D, Conner M, Lawson Z, Conner AC, Baker A, Cashmore Y, Kendrick R, Parslow RA. Wheatley M, et al. Among authors: wootten d. Biochem Soc Trans. 2007 Aug;35(Pt 4):717-20. doi: 10.1042/BST0350717. Biochem Soc Trans. 2007. PMID: 17635132 Review.

4

RAMPs and CGRP receptors.

Barwell J, Wootten D, Simms J, Hay DL, Poyner DR. Barwell J, et al. Among authors: wootten d. Adv Exp Med Biol. 2012;744:13-24. doi: 10.1007/978-1-4614-2364-5_2. Adv Exp Med Biol. 2012. PMID: 22434104 Review.

5

Diverse functional motifs within the three intracellular loops of the CGRP1 receptor.

Conner AC, Simms J, Conner MT, Wootten DL, Wheatley M, Poyner DR. Conner AC, et al. Biochemistry. 2006 Oct 31;45(43):12976-85. doi: 10.1021/bi0615801. Biochemistry. 2006. PMID: 17059214

6

Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT((a)) function.

Qi T, Dong M, Watkins HA, Wootten D, Miller LJ, Hay DL. Qi T, et al. Among authors: wootten d. Br J Pharmacol. 2013 Feb;168(3):644-57. doi: 10.1111/j.1476-5381.2012.02197.x. Br J Pharmacol. 2013. PMID: 22946511 Free PMC article.

7

Systematic analysis of the entire second extracellular loop of the V(1a) vasopressin receptor: key residues, conserved throughout a G-protein-coupled receptor family, identified.

Conner M, Hawtin SR, Simms J, Wootten D, Lawson Z, Conner AC, Parslow RA, Wheatley M. Conner M, et al. Among authors: wootten d. J Biol Chem. 2007 Jun 15;282(24):17405-12. doi: 10.1074/jbc.M702151200. Epub 2007 Apr 2. J Biol Chem. 2007. PMID: 17403667 Free article.

8

Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

Koole C, Wootten D, Simms J, Valant C, Sridhar R, Woodman OL, Miller LJ, Summers RJ, Christopoulos A, Sexton PM. Koole C, et al. Among authors: wootten d. Mol Pharmacol. 2010 Sep;78(3):456-65. doi: 10.1124/mol.110.065664. Epub 2010 Jun 14. Mol Pharmacol. 2010. PMID: 20547734 Free PMC article.

9

Receptor activity modifying proteins and their potential as drug targets.

Wootten DL, Simms J, Hay DL, Christopoulos A, Sexton PM. Wootten DL, et al. Prog Mol Biol Transl Sci. 2010;91:53-79. doi: 10.1016/S1877-1173(10)91003-X. Prog Mol Biol Transl Sci. 2010. PMID: 20691959 Review.

10

Modulation of the glucagon-like peptide-1 receptor signaling by naturally occurring and synthetic flavonoids.

Wootten D, Simms J, Koole C, Woodman OL, Summers RJ, Christopoulos A, Sexton PM. Wootten D, et al. J Pharmacol Exp Ther. 2011 Feb;336(2):540-50. doi: 10.1124/jpet.110.176362. Epub 2010 Nov 12. J Pharmacol Exp Ther. 2011. PMID: 21075839

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