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Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes.
Fodder K, Murthy M, Rizzu P, Toomey CE, Hasan R, Humphrey J, Raj T, Lunnon K, Mill J, Heutink P, Lashley T, Bettencourt C. Fodder K, et al. Among authors: lashley t. Acta Neuropathol. 2023 Jul;146(1):77-95. doi: 10.1007/s00401-023-02583-z. Epub 2023 May 7. Acta Neuropathol. 2023. PMID: 37149835 Free PMC article.
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies.
de Silva R, Lashley T, Strand C, Shiarli AM, Shi J, Tian J, Bailey KL, Davies P, Bigio EH, Arima K, Iseki E, Murayama S, Kretzschmar H, Neumann M, Lippa C, Halliday G, MacKenzie J, Ravid R, Dickson D, Wszolek Z, Iwatsubo T, Pickering-Brown SM, Holton J, Lees A, Revesz T, Mann DM. de Silva R, et al. Among authors: lashley t. Acta Neuropathol. 2006 Apr;111(4):329-40. doi: 10.1007/s00401-006-0048-x. Epub 2006 Mar 22. Acta Neuropathol. 2006. PMID: 16552612
TDP-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degeneration and in other neurodegenerative diseases: a degenerative process distinct from normal ageing.
Davidson Y, Amin H, Kelley T, Shi J, Tian J, Kumaran R, Lashley T, Lees AJ, DuPlessis D, Neary D, Snowden J, Akiyama H, Arai T, Hasegawa M, Bandopadhyay R, Sikkink S, Pickering-Brown S, Mann DM. Davidson Y, et al. Among authors: lashley t. Acta Neuropathol. 2009 Sep;118(3):359-69. doi: 10.1007/s00401-009-0526-z. Epub 2009 Mar 28. Acta Neuropathol. 2009. PMID: 19330339
Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies.
Ahmed Z, Doherty KM, Silveira-Moriyama L, Bandopadhyay R, Lashley T, Mamais A, Hondhamuni G, Wray S, Newcombe J, O'Sullivan SS, Wroe S, de Silva R, Holton JL, Lees AJ, Revesz T. Ahmed Z, et al. Among authors: lashley t. Acta Neuropathol. 2011 Oct;122(4):415-28. doi: 10.1007/s00401-011-0857-4. Epub 2011 Jul 21. Acta Neuropathol. 2011. PMID: 21773886
Transportin1: a marker of FTLD-FUS.
Brelstaff J, Lashley T, Holton JL, Lees AJ, Rossor MN, Bandopadhyay R, Revesz T. Brelstaff J, et al. Among authors: lashley t. Acta Neuropathol. 2011 Nov;122(5):591-600. doi: 10.1007/s00401-011-0863-6. Epub 2011 Aug 17. Acta Neuropathol. 2011. PMID: 21847626
Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia.
Fratta P, Poulter M, Lashley T, Rohrer JD, Polke JM, Beck J, Ryan N, Hensman D, Mizielinska S, Waite AJ, Lai MC, Gendron TF, Petrucelli L, Fisher EM, Revesz T, Warren JD, Collinge J, Isaacs AM, Mead S. Fratta P, et al. Among authors: lashley t. Acta Neuropathol. 2013 Sep;126(3):401-9. doi: 10.1007/s00401-013-1147-0. Epub 2013 Jul 2. Acta Neuropathol. 2013. PMID: 23818065 Free PMC article.
The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons.
Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MM, Spillantini MG. Iovino M, et al. Among authors: lashley t. Acta Neuropathol. 2014 Feb;127(2):283-95. doi: 10.1007/s00401-013-1219-1. Epub 2013 Nov 30. Acta Neuropathol. 2014. PMID: 24292008 Free PMC article.
192 results