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Mosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From the INTEGRAL-ILCCO Cohort Analysis.
Cheng C, Hong W, Li Y, Xiao X, McKay J, Han Y, Byun J, Peng B, Albanes D, Lam S, Tardon A, Chen C, Bojesen SE, Landi MT, Johansson M, Risch A, Bickeböller H, Wichmann HE, Christiani DC, Rennert G, Arnold S, Goodman G, Field JK, Davies MPA, Shete SS, Le Marchand L, Liu G, Hung RJ, Andrew AS, Kiemeney LA, Zhu M, Shen H, Zienolddiny S, Grankvist K, Johansson M, Cox A, Hong YC, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Brennan P, Li Y, Gorlova O, Gorlov I, Amos CI; INTEGRAL-ILCCO Lung Cancer Consortium. Cheng C, et al. Among authors: li y. J Thorac Oncol. 2023 Aug;18(8):1003-1016. doi: 10.1016/j.jtho.2023.05.001. Epub 2023 May 5. J Thorac Oncol. 2023. PMID: 37150255
A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers.
Amos CI, Pinney SM, Li Y, Kupert E, Lee J, de Andrade MA, Yang P, Schwartz AG, Fain PR, Gazdar A, Minna J, Wiest JS, Zeng D, Rothschild H, Mandal D, You M, Coons T, Gaba C, Bailey-Wilson JE, Anderson MW. Amos CI, et al. Among authors: li y. Cancer Res. 2010 Mar 15;70(6):2359-67. doi: 10.1158/0008-5472.CAN-09-3096. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215501 Free PMC article.
A recurrent mutation in PARK2 is associated with familial lung cancer.
Xiong D, Wang Y, Kupert E, Simpson C, Pinney SM, Gaba CR, Mandal D, Schwartz AG, Yang P, de Andrade M, Pikielny C, Byun J, Li Y, Stambolian D, Spitz MR, Liu Y, Amos CI, Bailey-Wilson JE, Anderson M, You M. Xiong D, et al. Among authors: li y. Am J Hum Genet. 2015 Feb 5;96(2):301-8. doi: 10.1016/j.ajhg.2014.12.016. Epub 2015 Jan 29. Am J Hum Genet. 2015. PMID: 25640678 Free PMC article.
Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer.
Poirier JG, Brennan P, McKay JD, Spitz MR, Bickeböller H, Risch A, Liu G, Le Marchand L, Tworoger S, McLaughlin J, Rosenberger A, Heinrich J, Brüske I, Muley T, Henderson BE, Wilkens LR, Zong X, Li Y, Hao K, Timens W, Bossé Y, Sin DD, Obeidat M, Amos CI, Hung RJ. Poirier JG, et al. Among authors: li y. Genet Epidemiol. 2015 Mar;39(3):197-206. doi: 10.1002/gepi.21882. Epub 2015 Jan 19. Genet Epidemiol. 2015. PMID: 25644374 Free PMC article.
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