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FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.
Nguyen-Dien GT, Kozul KL, Cui Y, Townsend B, Kulkarni PG, Ooi SS, Marzio A, Carrodus N, Zuryn S, Pagano M, Parton RG, Lazarou M, Millard SS, Taylor RW, Collins BM, Jones MJ, Pagan JK. Nguyen-Dien GT, et al. Among authors: lazarou m. EMBO J. 2023 Jul 3;42(13):e112767. doi: 10.15252/embj.2022112767. Epub 2023 May 10. EMBO J. 2023. PMID: 37161784 Free PMC article.
Quality Control: Maintaining molecular order and preventing cellular chaos.
Neal S, Ohtake F, Cuervo AM, Hegde RS, Jakob U, Lazarou M, Gilbert WV, Chen ZJ, Tooze SA, Haber JE, Walters KJ, Hartl FU. Neal S, et al. Among authors: lazarou m. Mol Cell. 2022 Apr 21;82(8):1390-1397. doi: 10.1016/j.molcel.2022.04.002. Mol Cell. 2022. PMID: 35452608 Free article.
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy.
Bernardini JP, Brouwer JM, Tan IK, Sandow JJ, Huang S, Stafford CA, Bankovacki A, Riffkin CD, Wardak AZ, Czabotar PE, Lazarou M, Dewson G. Bernardini JP, et al. Among authors: lazarou m. EMBO J. 2019 Jan 15;38(2):e99916. doi: 10.15252/embj.201899916. Epub 2018 Dec 20. EMBO J. 2019. PMID: 30573668 Free PMC article.
Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.
Nguyen TN, Padman BS, Lazarou M. Nguyen TN, et al. Among authors: lazarou m. Trends Cell Biol. 2016 Oct;26(10):733-744. doi: 10.1016/j.tcb.2016.05.008. Epub 2016 Jun 10. Trends Cell Biol. 2016. PMID: 27291334 Review.
88 results