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Comparison of tumor-informed and tumor-naïve sequencing assays for ctDNA detection in breast cancer.
Santonja A, Cooper WN, Eldridge MD, Edwards PAW, Morris JA, Edwards AR, Zhao H, Heider K, Couturier DL, Vijayaraghavan A, Mennea P, Ditter EJ, Smith CG, Boursnell C, Manzano García R, Rueda OM, Beddowes E, Biggs H, Sammut SJ, Rosenfeld N, Caldas C, Abraham JE, Gale D. Santonja A, et al. Among authors: couturier dl. EMBO Mol Med. 2023 Jun 7;15(6):e16505. doi: 10.15252/emmm.202216505. Epub 2023 May 10. EMBO Mol Med. 2023. PMID: 37161793 Free PMC article.
Metabolic Imaging Detects Resistance to PI3Kα Inhibition Mediated by Persistent FOXM1 Expression in ER+ Breast Cancer.
Ros S, Wright AJ, D'Santos P, Hu DE, Hesketh RL, Lubling Y, Georgopoulou D, Lerda G, Couturier DL, Razavi P, Pelossof R, Batra AS, Mannion E, Lewis DY, Martin A, Baird RD, Oliveira M, de Boo LW, Linn SC, Scaltriti M, Rueda OM, Bruna A, Caldas C, Brindle KM. Ros S, et al. Among authors: couturier dl. Cancer Cell. 2020 Oct 12;38(4):516-533.e9. doi: 10.1016/j.ccell.2020.08.016. Epub 2020 Sep 24. Cancer Cell. 2020. PMID: 32976773 Free PMC article.
Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients.
Mouliere F, Smith CG, Heider K, Su J, van der Pol Y, Thompson M, Morris J, Wan JCM, Chandrananda D, Hadfield J, Grzelak M, Hudecova I, Couturier DL, Cooper W, Zhao H, Gale D, Eldridge M, Watts C, Brindle K, Rosenfeld N, Mair R. Mouliere F, et al. Among authors: couturier dl. EMBO Mol Med. 2021 Aug 9;13(8):e12881. doi: 10.15252/emmm.202012881. Epub 2021 Jul 22. EMBO Mol Med. 2021. PMID: 34291583 Free PMC article.
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer.
Martins FC, Couturier DL, de Santiago I, Sauer CM, Vias M, Angelova M, Sanders D, Piskorz A, Hall J, Hosking K, Amirthanayagam A, Cosulich S, Carnevalli L, Davies B, Watkins TBK, Funingana IG, Bolton H, Haldar K, Latimer J, Baldwin P, Crawford R, Eldridge M, Basu B, Jimenez-Linan M, Mcpherson AW, McGranahan N, Litchfield K, Shah SP, McNeish I, Caldas C, Evan G, Swanton C, Brenton JD. Martins FC, et al. Among authors: couturier dl. Nat Commun. 2022 Oct 26;13(1):6360. doi: 10.1038/s41467-022-33870-0. Nat Commun. 2022. PMID: 36289203 Free PMC article.
Molecular landscape and functional characterization of centrosome amplification in ovarian cancer.
Sauer CM, Hall JA, Couturier DL, Bradley T, Piskorz AM, Griffiths J, Sawle A, Eldridge MD, Smith P, Hosking K, Reinius MAV, Morrill Gavarró L, Mes-Masson AM, Ennis D, Millan D, Hoyle A, McNeish IA, Jimenez-Linan M, Martins FC, Tischer J, Vias M, Brenton JD. Sauer CM, et al. Among authors: couturier dl. Nat Commun. 2023 Oct 16;14(1):6505. doi: 10.1038/s41467-023-41840-3. Nat Commun. 2023. PMID: 37845213 Free PMC article.
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.
Nagarajan S, Rao SV, Sutton J, Cheeseman D, Dunn S, Papachristou EK, Prada JG, Couturier DL, Kumar S, Kishore K, Chilamakuri CSR, Glont SE, Archer Goode E, Brodie C, Guppy N, Natrajan R, Bruna A, Caldas C, Russell A, Siersbæk R, Yusa K, Chernukhin I, Carroll JS. Nagarajan S, et al. Among authors: couturier dl. Nat Genet. 2020 Feb;52(2):187-197. doi: 10.1038/s41588-019-0541-5. Epub 2020 Jan 6. Nat Genet. 2020. PMID: 31913353 Free PMC article.
Author Correction: ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.
Nagarajan S, Rao SV, Sutton J, Cheeseman D, Dunn S, Papachristou EK, Prada JG, Couturier DL, Kumar S, Kishore K, Chilamakuri CSR, Glont SE, Goode EA, Brodie C, Guppy N, Natrajan R, Bruna A, Caldas C, Russell A, Siersbæk R, Yusa K, Chernukhin I, Carroll JS. Nagarajan S, et al. Among authors: couturier dl. Nat Genet. 2020 Mar;52(3):354. doi: 10.1038/s41588-020-0582-9. Nat Genet. 2020. PMID: 32005967
Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.
Jiménez-Sánchez A, Cybulska P, Mager KL, Koplev S, Cast O, Couturier DL, Memon D, Selenica P, Nikolovski I, Mazaheri Y, Bykov Y, Geyer FC, Macintyre G, Gavarró LM, Drews RM, Gill MB, Papanastasiou AD, Sosa RE, Soslow RA, Walther T, Shen R, Chi DS, Park KJ, Hollmann T, Reis-Filho JS, Markowetz F, Beltrao P, Vargas HA, Zamarin D, Brenton JD, Snyder A, Weigelt B, Sala E, Miller ML. Jiménez-Sánchez A, et al. Among authors: couturier dl. Nat Genet. 2020 Jun;52(6):582-593. doi: 10.1038/s41588-020-0630-5. Epub 2020 Jun 1. Nat Genet. 2020. PMID: 32483290 Free PMC article.
47 results