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Structure of the human κ-opioid receptor in complex with JDTic.
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, Stevens RC. Wu H, et al. Among authors: huang xp. Nature. 2012 Mar 21;485(7398):327-32. doi: 10.1038/nature10939. Nature. 2012. PMID: 22437504 Free PMC article.
Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists.
Kim J, Kim Y, Tae J, Yeom M, Moon B, Huang XP, Roth BL, Lee K, Rhim H, Choo IH, Chong Y, Keum G, Nam G, Choo H. Kim J, et al. Among authors: huang xp. ChemMedChem. 2013 Nov;8(11):1855-64. doi: 10.1002/cmdc.201300240. Epub 2013 Sep 3. ChemMedChem. 2013. PMID: 24039134
Molecular control of δ-opioid receptor signalling.
Fenalti G, Giguere PM, Katritch V, Huang XP, Thompson AA, Cherezov V, Roth BL, Stevens RC. Fenalti G, et al. Among authors: huang xp. Nature. 2014 Feb 13;506(7487):191-6. doi: 10.1038/nature12944. Epub 2014 Jan 12. Nature. 2014. PMID: 24413399 Free PMC article.
A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).
Kaniskan HÜ, Szewczyk MM, Yu Z, Eram MS, Yang X, Schmidt K, Luo X, Dai M, He F, Zang I, Lin Y, Kennedy S, Li F, Dobrovetsky E, Dong A, Smil D, Min SJ, Landon M, Lin-Jones J, Huang XP, Roth BL, Schapira M, Atadja P, Barsyte-Lovejoy D, Arrowsmith CH, Brown PJ, Zhao K, Jin J, Vedadi M. Kaniskan HÜ, et al. Among authors: huang xp. Angew Chem Int Ed Engl. 2015 Apr 20;54(17):5166-70. doi: 10.1002/anie.201412154. Epub 2015 Feb 27. Angew Chem Int Ed Engl. 2015. PMID: 25728001 Free PMC article.
In silico design of novel probes for the atypical opioid receptor MRGPRX2.
Lansu K, Karpiak J, Liu J, Huang XP, McCorvy JD, Kroeze WK, Che T, Nagase H, Carroll FI, Jin J, Shoichet BK, Roth BL. Lansu K, et al. Among authors: huang xp. Nat Chem Biol. 2017 May;13(5):529-536. doi: 10.1038/nchembio.2334. Epub 2017 Mar 13. Nat Chem Biol. 2017. PMID: 28288109 Free PMC article.
356 results