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Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model.
Abudahab S, Kronfol MM, Dozmorov MG, Campbell T, Jahr FM, Nguyen J, AlAzzeh O, Al Saeedy DY, Victor A, Lee S, Malay S, Lapato DM, Halquist MS, McRae M, Deshpande LS, Slattum PW, Price ET, McClay JL. Abudahab S, et al. Among authors: mcclay jl. Geroscience. 2024 Apr 1. doi: 10.1007/s11357-024-01137-9. Online ahead of print. Geroscience. 2024. PMID: 38558216
Ketamine Produces Antidepressant Effects by Inhibiting Histone Deacetylases and Upregulating Hippocampal Brain-Derived Neurotrophic Factor Levels in a Diisopropyl Fluorophosphate-Based Rat Model of Gulf War Illness.
Ribeiro-Davis A, Al Saeedy DY, Jahr FM, Hawkins E, McClay JL, Deshpande LS. Ribeiro-Davis A, et al. Among authors: mcclay jl. J Pharmacol Exp Ther. 2024 Jan 17;388(2):647-654. doi: 10.1124/jpet.123.001824. J Pharmacol Exp Ther. 2024. PMID: 37863487 Free PMC article.
The Aryl Hydrocarbon Receptor, Epigenetics and the Aging Process.
Abudahab S, Price ET, Dozmorov MG, Deshpande LS, McClay JL. Abudahab S, et al. Among authors: mcclay jl. J Nutr Health Aging. 2023;27(4):291-300. doi: 10.1007/s12603-023-1908-1. J Nutr Health Aging. 2023. PMID: 37170437 Free PMC article.
Epigenetics in drug disposition & drug therapy: symposium report of the 24th North American meeting of the International Society for the Study of Xenobiotics (ISSX).
Maldonato BJ, Vergara AG, Yadav J, Glass SM, Paragas EM, Li D, Lazarus P, McClay JL, Ning B, Daly AK, Russell LE. Maldonato BJ, et al. Among authors: mcclay jl. Drug Metab Rev. 2022 Aug;54(3):318-330. doi: 10.1080/03602532.2022.2101662. Epub 2022 Aug 24. Drug Metab Rev. 2022. PMID: 35876105 Free PMC article. Review.
Epigenetic regulation of drug metabolism in aging.
McClay JL. McClay JL. Aging (Albany NY). 2021 Jul 11;13(13):16898-16899. doi: 10.18632/aging.203312. Epub 2021 Jul 11. Aging (Albany NY). 2021. PMID: 34251355 Free PMC article. No abstract available.
57 results