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Page 1
Genetic Profiling of Sodium Channels in Diabetic Painful and Painless and Idiopathic Painful and Painless Neuropathies.
Almomani R, Sopacua M, Marchi M, Ślęczkowska M, Lindsey P, de Greef BTA, Hoeijmakers JGJ, Salvi E, Merkies ISJ, Ferdousi M, Malik RA, Ziegler D, Derks KWJ, Boenhof G, Martinelli-Boneschi F, Cazzato D, Lombardi R, Dib-Hajj S, Waxman SG, Smeets HJM, Gerrits MM, Faber CG, Lauria G, On Behalf Of The Propane Study Group. Almomani R, et al. Among authors: derks kwj. Int J Mol Sci. 2023 May 5;24(9):8278. doi: 10.3390/ijms24098278. Int J Mol Sci. 2023. PMID: 37175987 Free PMC article.
Clustering of Cardiac Transcriptome Profiles Reveals Unique: Subgroups of Dilated Cardiomyopathy Patients.
Verdonschot JAJ, Wang P, Derks KWJ, Adriaens ME, Stroeks SLVM, Henkens MTHM, Raafs AG, Sikking M, de Koning B, van den Wijngaard A, Krapels IPC, Nabben M, Brunner HG, Heymans SRB. Verdonschot JAJ, et al. Among authors: derks kwj. JACC Basic Transl Sci. 2023 Feb 1;8(4):406-418. doi: 10.1016/j.jacbts.2022.10.010. eCollection 2023 Apr. JACC Basic Transl Sci. 2023. PMID: 37138803 Free PMC article.
Genome-wide RNA polymerase stalling shapes the transcriptome during aging.
Gyenis A, Chang J, Demmers JJPG, Bruens ST, Barnhoorn S, Brandt RMC, Baar MP, Raseta M, Derks KWJ, Hoeijmakers JHJ, Pothof J. Gyenis A, et al. Among authors: derks kwj. Nat Genet. 2023 Feb;55(2):268-279. doi: 10.1038/s41588-022-01279-6. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658433 Free PMC article.
Pathogenic neurofibromatosis type 1 (NF1) RNA splicing resolved by targeted RNAseq.
Koster R, Brandão RD, Tserpelis D, van Roozendaal CEP, van Oosterhoud CN, Claes KBM, Paulussen ADC, Sinnema M, Vreeburg M, van der Schoot V, Stumpel CTRM, Broen MPG, Spruijt L, Jongmans MCJ, Lesnik Oberstein SAJ, Plomp AS, Misra-Isrie M, Duijkers FA, Louwers MJ, Szklarczyk R, Derks KWJ, Brunner HG, van den Wijngaard A, van Geel M, Blok MJ. Koster R, et al. Among authors: derks kwj. NPJ Genom Med. 2021 Nov 15;6(1):95. doi: 10.1038/s41525-021-00258-w. NPJ Genom Med. 2021. PMID: 34782607 Free PMC article.
Phenotypic clustering of dilated cardiomyopathy patients highlights important pathophysiological differences.
Verdonschot JAJ, Merlo M, Dominguez F, Wang P, Henkens MTHM, Adriaens ME, Hazebroek MR, Masè M, Escobar LE, Cobas-Paz R, Derks KWJ, van den Wijngaard A, Krapels IPC, Brunner HG, Sinagra G, Garcia-Pavia P, Heymans SRB. Verdonschot JAJ, et al. Among authors: derks kwj. Eur Heart J. 2021 Jan 7;42(2):162-174. doi: 10.1093/eurheartj/ehaa841. Eur Heart J. 2021. PMID: 33156912 Free PMC article.
Cardiac Inflammation Impedes Response to Cardiac Resynchronization Therapy in Patients With Idiopathic Dilated Cardiomyopathy.
Verdonschot JAJ, Merken JJ, van Stipdonk AMW, Pliger P, Derks KWJ, Wang P, Henkens MTHM, van Paassen P, Abdul Hamid MA, van Empel VPM, Knackstedt C, Luermans JGLM, Crijns HJGM, Brunner-La Rocca HP, Brunner HG, Poelzl G, Vernooy K, Heymans SRB, Hazebroek MR. Verdonschot JAJ, et al. Among authors: derks kwj. Circ Arrhythm Electrophysiol. 2020 Nov;13(11):e008727. doi: 10.1161/CIRCEP.120.008727. Epub 2020 Sep 30. Circ Arrhythm Electrophysiol. 2020. PMID: 32997547
Titin cardiomyopathy leads to altered mitochondrial energetics, increased fibrosis and long-term life-threatening arrhythmias.
Verdonschot JAJ, Hazebroek MR, Derks KWJ, Barandiarán Aizpurua A, Merken JJ, Wang P, Bierau J, van den Wijngaard A, Schalla SM, Abdul Hamid MA, van Bilsen M, van Empel VPM, Knackstedt C, Brunner-La Rocca HP, Brunner HG, Krapels IPC, Heymans SRB. Verdonschot JAJ, et al. Among authors: derks kwj. Eur Heart J. 2018 Mar 7;39(10):864-873. doi: 10.1093/eurheartj/ehx808. Eur Heart J. 2018. PMID: 29377983
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ. Baar MP, et al. Among authors: derks kwj. Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031. Cell. 2017. PMID: 28340339 Free PMC article.
Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson's Disease.
Sepe S, Milanese C, Gabriels S, Derks KW, Payan-Gomez C, van IJcken WF, Rijksen YM, Nigg AL, Moreno S, Cerri S, Blandini F, Hoeijmakers JH, Mastroberardino PG. Sepe S, et al. Cell Rep. 2016 May 31;15(9):1866-75. doi: 10.1016/j.celrep.2016.04.071. Epub 2016 May 19. Cell Rep. 2016. PMID: 27210754 Free PMC article.
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