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Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer.
Turner MA, Cox KE, Liu S, Neel N, Amirfakhri S, Nishino H, Hosseini M, Alcantara JA, Abd El-Hafeez AA, Lwin TM, Mallya K, Pisegna JR, Singh SK, Ghosh P, Hoffman RM, Batra SK, Bouvet M. Turner MA, et al. Among authors: hoffman rm. Curr Issues Mol Biol. 2023 Apr 11;45(4):3347-3358. doi: 10.3390/cimb45040219. Curr Issues Mol Biol. 2023. PMID: 37185743 Free PMC article.
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation.
Aoki Y, Han Q, Tome Y, Yamamoto J, Kubota Y, Masaki N, Obara K, Hamada K, Wang JD, Inubushi S, Bouvet M, Clarke SG, Nishida K, Hoffman RM. Aoki Y, et al. Among authors: hoffman rm. Front Oncol. 2022 Nov 3;12:1009548. doi: 10.3389/fonc.2022.1009548. eCollection 2022. Front Oncol. 2022. PMID: 36408173 Free PMC article.
Recombinant Methioninase Decreased the Effective Dose of Irinotecan by 15-fold Against Colon Cancer Cells: A Strategy for Effective Low-toxicity Treatment of Colon Cancer.
Sato M, Han Q, Kubota Y, Baranov A, Ardjmand D, Mizuta K, Morinaga S, Kang BM, Kobayashi N, Bouvet M, Ichikawa Y, Nakajima A, Hoffman RM. Sato M, et al. Among authors: hoffman rm. Anticancer Res. 2024 Jan;44(1):31-35. doi: 10.21873/anticanres.16785. Anticancer Res. 2024. PMID: 38159986
Methionine restriction of glioma does not induce MGMT and greatly improves temozolomide efficacy in an orthotopic nude-mouse model: A potential curable approach to a clinically-incurable disease.
Kubota Y, Aoki Y, Masaki N, Obara K, Hamada K, Han Q, Bouvet M, Tsunoda T, Hoffman RM. Kubota Y, et al. Among authors: hoffman rm. Biochem Biophys Res Commun. 2024 Feb 5;695:149418. doi: 10.1016/j.bbrc.2023.149418. Epub 2023 Dec 25. Biochem Biophys Res Commun. 2024. PMID: 38176171 Free article.
Methionine Dependence of Hair Maintenance in C57BL/6 Mice.
Kubota Y, Varshney N, Kobayashi K, Tsunoda T, Hoffman RM. Kubota Y, et al. Among authors: hoffman rm. In Vivo. 2024 May-Jun;38(3):1199-1202. doi: 10.21873/invivo.13555. In Vivo. 2024. PMID: 38688645 Free PMC article.
Targeting Methionine Addiction of Cancer Cells with Methioninase.
Pokrovsky VS, Qoura LA, Demidova EA, Han Q, Hoffman RM. Pokrovsky VS, et al. Among authors: hoffman rm. Biochemistry (Mosc). 2023 Jul;88(7):944-952. doi: 10.1134/S0006297923070076. Biochemistry (Mosc). 2023. PMID: 37751865 Review.
1,474 results