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Page 1
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes.
McAllan L, Baranasic D, Villicaña S, Brown S, Zhang W, Lehne B, Adamo M, Jenkinson A, Elkalaawy M, Mohammadi B, Hashemi M, Fernandes N, Lambie N, Williams R, Christiansen C, Yang Y, Zudina L, Lagou V, Tan S, Castillo-Fernandez J, King JWD, Soong R, Elliott P, Scott J, Prokopenko I, Cebola I, Loh M, Lenhard B, Batterham RL, Bell JT, Chambers JC, Kooner JS, Scott WR. McAllan L, et al. Among authors: cebola i. Nat Commun. 2023 May 15;14(1):2784. doi: 10.1038/s41467-023-38439-z. Nat Commun. 2023. PMID: 37188674 Free PMC article.
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.
Miguel-Escalada I, Bonàs-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G, Javierre BM, Rolando DMY, Farabella I, Morgan CC, García-Hurtado J, Beucher A, Morán I, Pasquali L, Ramos-Rodríguez M, Appel EVR, Linneberg A, Gjesing AP, Witte DR, Pedersen O, Grarup N, Ravassard P, Torrents D, Mercader JM, Piemonti L, Berney T, de Koning EJP, Kerr-Conte J, Pattou F, Fedko IO, Groop L, Prokopenko I, Hansen T, Marti-Renom MA, Fraser P, Ferrer J. Miguel-Escalada I, et al. Among authors: cebola i. Nat Genet. 2019 Jul;51(7):1137-1148. doi: 10.1038/s41588-019-0457-0. Epub 2019 Jun 28. Nat Genet. 2019. PMID: 31253982 Free PMC article.
Epigenetics of Hepatic Insulin Resistance.
Maude H, Sanchez-Cabanillas C, Cebola I. Maude H, et al. Among authors: cebola i. Front Endocrinol (Lausanne). 2021 May 11;12:681356. doi: 10.3389/fendo.2021.681356. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34046015 Free PMC article. Review.
GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.
Dixon PH, Levine AP, Cebola I, Chan MMY, Amin AS, Aich A, Mozere M, Maude H, Mitchell AL, Zhang J; NIHR BioResource; Genomics England Research Consortium Collaborators; Chambers J, Syngelaki A, Donnelly J, Cooley S, Geary M, Nicolaides K, Thorsell M, Hague WM, Estiu MC, Marschall HU, Gale DP, Williamson C. Dixon PH, et al. Among authors: cebola i. Nat Commun. 2022 Aug 17;13(1):4840. doi: 10.1038/s41467-022-29931-z. Nat Commun. 2022. PMID: 35977952 Free PMC article.
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice.
Ramos-Pittol JM, Fernandes-Freitas I, Milona A, Manchishi SM, Rainbow K, Lam BYH, Tadross JA, Beucher A, Colledge WH, Cebola I, Murphy KG, Miguel-Aliaga I, Yeo GSH, Dhillo WS, Owen BM. Ramos-Pittol JM, et al. Among authors: cebola i. Nat Commun. 2023 May 29;14(1):3076. doi: 10.1038/s41467-023-38618-y. Nat Commun. 2023. PMID: 37248237 Free PMC article.
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants.
Pasquali L, Gaulton KJ, Rodríguez-Seguí SA, Mularoni L, Miguel-Escalada I, Akerman İ, Tena JJ, Morán I, Gómez-Marín C, van de Bunt M, Ponsa-Cobas J, Castro N, Nammo T, Cebola I, García-Hurtado J, Maestro MA, Pattou F, Piemonti L, Berney T, Gloyn AL, Ravassard P, Skarmeta JLG, Müller F, McCarthy MI, Ferrer J. Pasquali L, et al. Among authors: cebola i. Nat Genet. 2014 Feb;46(2):136-143. doi: 10.1038/ng.2870. Epub 2014 Jan 12. Nat Genet. 2014. PMID: 24413736 Free PMC article.
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice.
Paterson HAB, Yu S, Artigas N, Prado MA, Haberman N, Wang YF, Jobbins AM, Pahita E, Mokochinski J, Hall Z, Guerin M, Paulo JA, Ng SS, Villarroya F, Rashid ST, Le Goff W, Lenhard B, Cebola I, Finley D, Gygi SP, Sibley CR, Vernia S. Paterson HAB, et al. Among authors: cebola i. Nat Metab. 2022 Dec;4(12):1812-1829. doi: 10.1038/s42255-022-00681-y. Epub 2022 Dec 19. Nat Metab. 2022. PMID: 36536133 Free PMC article.
Zooming into process-specific risk.
Maude H, Cebola I. Maude H, et al. Among authors: cebola i. Nat Metab. 2023 May;5(5):730-731. doi: 10.1038/s42255-023-00770-6. Nat Metab. 2023. PMID: 37253880 No abstract available.
30 results