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Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans.
Gao C, Amador C, Walker RM, Campbell A, Madden RA, Adams MJ, Bai X, Liu Y, Li M, Hayward C, Porteous DJ, Shen X, Evans KL, Haley CS, McIntosh AM, Navarro P, Zeng Y. Gao C, et al. Among authors: mcintosh am. Genome Biol. 2023 May 15;24(1):117. doi: 10.1186/s13059-023-02953-6. Genome Biol. 2023. PMID: 37189164 Free PMC article.
The effects of a neuregulin 1 variant on white matter density and integrity.
McIntosh AM, Moorhead TW, Job D, Lymer GK, Muñoz Maniega S, McKirdy J, Sussmann JE, Baig BJ, Bastin ME, Porteous D, Evans KL, Johnstone EC, Lawrie SM, Hall J. McIntosh AM, et al. Mol Psychiatry. 2008 Nov;13(11):1054-9. doi: 10.1038/sj.mp.4002103. Epub 2007 Oct 9. Mol Psychiatry. 2008. PMID: 17925794
DISC1 in schizophrenia: genetic mouse models and human genomic imaging.
Johnstone M, Thomson PA, Hall J, McIntosh AM, Lawrie SM, Porteous DJ. Johnstone M, et al. Among authors: mcintosh am. Schizophr Bull. 2011 Jan;37(1):14-20. doi: 10.1093/schbul/sbq135. Epub 2010 Dec 13. Schizophr Bull. 2011. PMID: 21149852 Free PMC article. Review.
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins.
Eykelenboom JE, Briggs GJ, Bradshaw NJ, Soares DC, Ogawa F, Christie S, Malavasi EL, Makedonopoulou P, Mackie S, Malloy MP, Wear MA, Blackburn EA, Bramham J, McIntosh AM, Blackwood DH, Muir WJ, Porteous DJ, Millar JK. Eykelenboom JE, et al. Among authors: mcintosh am. Hum Mol Genet. 2012 Aug 1;21(15):3374-86. doi: 10.1093/hmg/dds169. Epub 2012 Apr 30. Hum Mol Genet. 2012. PMID: 22547224 Free PMC article.
Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder.
Whalley HC, Papmeyer M, Romaniuk L, Sprooten E, Johnstone EC, Hall J, Lawrie SM, Evans KL, Blumberg HP, Sussmann JE, McIntosh AM. Whalley HC, et al. Among authors: mcintosh am. Neuropsychopharmacology. 2012 Nov;37(12):2720-9. doi: 10.1038/npp.2012.137. Epub 2012 Aug 1. Neuropsychopharmacology. 2012. PMID: 22850735 Free PMC article.
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
Thomson PA, Parla JS, McRae AF, Kramer M, Ramakrishnan K, Yao J, Soares DC, McCarthy S, Morris SW, Cardone L, Cass S, Ghiban E, Hennah W, Evans KL, Rebolini D, Millar JK, Harris SE, Starr JM, MacIntyre DJ; Generation Scotland; McIntosh AM, Watson JD, Deary IJ, Visscher PM, Blackwood DH, McCombie WR, Porteous DJ. Thomson PA, et al. Among authors: mcintosh am. Mol Psychiatry. 2014 Jun;19(6):668-75. doi: 10.1038/mp.2013.68. Epub 2013 Jun 4. Mol Psychiatry. 2014. PMID: 23732877 Free PMC article.
553 results