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Synaptic oligomeric tau in Alzheimer's disease - A potential culprit in the spread of tau pathology through the brain.
Colom-Cadena M, Davies C, Sirisi S, Lee JE, Simzer EM, Tzioras M, Querol-Vilaseca M, Sánchez-Aced É, Chang YY, Holt K, McGeachan RI, Rose J, Tulloch J, Wilkins L, Smith C, Andrian T, Belbin O, Pujals S, Horrocks MH, Lleó A, Spires-Jones TL. Colom-Cadena M, et al. Among authors: holt k. Neuron. 2023 Jul 19;111(14):2170-2183.e6. doi: 10.1016/j.neuron.2023.04.020. Epub 2023 May 15. Neuron. 2023. PMID: 37192625 Free article.
p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.
Taylor LW, Simzer EM, Pimblett C, Lacey-Solymar OTT, McGeachan RI, Meftah S, Rose JL, Spires-Jones MP, Holt K, Catterson JH, Koch H, Liaquat I, Clarke JH, Skidmore J, Smith C, Booker SA, Brennan PM, Spires-Jones TL, Durrant CS. Taylor LW, et al. Among authors: holt k. Acta Neuropathol. 2024 Jan 4;147(1):7. doi: 10.1007/s00401-023-02667-w. Acta Neuropathol. 2024. PMID: 38175261 Free PMC article.
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.
Colom-Cadena M, Toombs J, Simzer E, Holt K, McGeachan R, Tulloch J, Jackson RJ, Catterson JH, Spires-Jones MP, Rose J, Waybright L, Caggiano AO, King D, Gobbo F, Davies C, Hooley M, Dunnett S, Tempelaar R, Meftah S, Tzioras M, Hamby ME, Izzo NJ, Catalano SM, Durrant CS, Smith C, Dando O, Spires-Jones TL. Colom-Cadena M, et al. Among authors: holt k. Acta Neuropathol. 2024 Feb 6;147(1):32. doi: 10.1007/s00401-023-02679-6. Acta Neuropathol. 2024. PMID: 38319380 Free PMC article.
Specialist physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 randomised controlled trial.
Nielsen G, Stone J, Lee TC, Goldstein LH, Marston L, Hunter RM, Carson A, Holt K, Marsden J, Le Novere M, Nazareth I, Noble H, Reuber M, Strudwick AM, Santana Suarez B, Edwards MJ; Physio4FMD study group. Nielsen G, et al. Among authors: holt k. Lancet Neurol. 2024 May 16:S1474-4422(24)00135-2. doi: 10.1016/S1474-4422(24)00135-2. Online ahead of print. Lancet Neurol. 2024. PMID: 38768621
Genomic diversity and antimicrobial resistance in clinical Klebsiella pneumoniae isolates from tertiary hospitals in Southern Ghana.
Mills RO, Dadzie I, Le-Viet T, Baker DJ, Addy HPK, Akwetey SA, Donkoh IE, Quansah E, Semanshia PS, Morgan J, Mensah A, Adade NE, Ampah EO, Owusu E, Mwintige P, Amoako EO, Spadar A, Holt KE, Foster-Nyarko E. Mills RO, et al. Among authors: holt ke. J Antimicrob Chemother. 2024 May 16:dkae123. doi: 10.1093/jac/dkae123. Online ahead of print. J Antimicrob Chemother. 2024. PMID: 38751093
Vaccine value profile for Klebsiella pneumoniae.
Dangor Z, Benson N, Berkley JA, Bielicki J, Bijsma MW, Broad J, Buurman ET, Cross A, Duffy EM, Holt KE, Iroh Tam PY, Jit M, Karampatsas K, Katwere M, Kwatra G, Laxminarayan R, Le Doare K, Mboizi R, Micoli F, Moore CE, Nakabembe E, Naylor NR, O'Brien S, Olwagen C, Reddy D, Rodrigues C, Rosen DA, Sadarangani M, Srikantiah P, Tennant SM, Hasso-Agopsowicz M, Madhi SA. Dangor Z, et al. Among authors: holt ke. Vaccine. 2024 Mar 18:S0264-410X(24)00248-2. doi: 10.1016/j.vaccine.2024.02.072. Online ahead of print. Vaccine. 2024. PMID: 38503661 Free article.
Recent advances in modelling Shigella infection.
Miles SL, Holt KE, Mostowy S. Miles SL, et al. Among authors: holt ke. Trends Microbiol. 2024 Feb 28:S0966-842X(24)00044-1. doi: 10.1016/j.tim.2024.02.004. Online ahead of print. Trends Microbiol. 2024. PMID: 38423917 Free article. Review.
818 results