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Synaptic oligomeric tau in Alzheimer's disease - A potential culprit in the spread of tau pathology through the brain.
Colom-Cadena M, Davies C, Sirisi S, Lee JE, Simzer EM, Tzioras M, Querol-Vilaseca M, Sánchez-Aced É, Chang YY, Holt K, McGeachan RI, Rose J, Tulloch J, Wilkins L, Smith C, Andrian T, Belbin O, Pujals S, Horrocks MH, Lleó A, Spires-Jones TL. Colom-Cadena M, et al. Among authors: sirisi s. Neuron. 2023 Jul 19;111(14):2170-2183.e6. doi: 10.1016/j.neuron.2023.04.020. Epub 2023 May 15. Neuron. 2023. PMID: 37192625 Free article.
Amyloid precursor protein 𝛽CTF accumulates in synapses in sporadic and genetic forms of Alzheimer's disease.
Ferrer-Raventós P, Puertollano-Martín D, Querol-Vilaseca M, Sánchez-Aced É, Valle-Tamayo N, Cervantes-Gonzalez A, Nuñez-Llaves R, Pegueroles J, Dols-Icardo O, Iulita MF, Aldecoa I, Molina-Porcel L, Sánchez-Valle R, Fortea J, Belbin O, Sirisi S, Lleó A. Ferrer-Raventós P, et al. Among authors: sirisi s. Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12879. doi: 10.1111/nan.12879. Neuropathol Appl Neurobiol. 2023. PMID: 36702749
Neuropathology of a patient with Alzheimer disease treated with low doses of verubecestat.
Querol-Vilaseca M, Sirisi S, Molina-Porcel L, Molina B, Pegueroles J, Ferrer-Raventós P, Nuñez-Llaves R, Dols-Icardo O, Balasa M, Iulita MF, Blesa R, Belbin O, Clarimon J, Fortea J, Gelpi E, Sánchez-Valle R, Lleó A. Querol-Vilaseca M, et al. Among authors: sirisi s. Neuropathol Appl Neurobiol. 2022 Apr;48(3):e12781. doi: 10.1111/nan.12781. Epub 2021 Dec 7. Neuropathol Appl Neurobiol. 2022. PMID: 34825396
Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration.
Cervantes González A, Irwin DJ, Alcolea D, McMillan CT, Chen-Plotkin A, Wolk D, Sirisi S, Dols-Icardo O, Querol-Vilaseca M, Illán-Gala I, Santos-Santos MA, Fortea J, Lee EB, Trojanowski JQ, Grossman M, Lleó A, Belbin O. Cervantes González A, et al. Among authors: sirisi s. Mol Neurodegener. 2022 Apr 8;17(1):29. doi: 10.1186/s13024-022-00534-y. Mol Neurodegener. 2022. PMID: 35395770 Free PMC article.
Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis.
Dols-Icardo O, Montal V, Sirisi S, López-Pernas G, Cervera-Carles L, Querol-Vilaseca M, Muñoz L, Belbin O, Alcolea D, Molina-Porcel L, Pegueroles J, Turón-Sans J, Blesa R, Lleó A, Fortea J, Rojas-García R, Clarimón J. Dols-Icardo O, et al. Among authors: sirisi s. Neurol Neuroimmunol Neuroinflamm. 2020 Jul 15;7(5):e829. doi: 10.1212/NXI.0000000000000829. Print 2020 Sep. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32669313 Free PMC article.
Myelin loss in C9orf72 hexanucleotide expansion carriers.
Sirisi S, Querol-Vilaseca M, Dols-Icardo O, Pegueroles J, Montal V, Muñoz L, Torres S, Ferrer-Raventós P, Iulita MF, Sánchez-Aced É, Blesa R, Illán-Gala I, Molina-Porcel L, Borrego-Ecija S, Sánchez-Valle R, Clarimon J, Belbin O, Fortea J, Lleó A. Sirisi S, et al. J Neurosci Res. 2022 Oct;100(10):1862-1875. doi: 10.1002/jnr.25100. Epub 2022 Jun 29. J Neurosci Res. 2022. PMID: 35766328
VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome.
Lleó A, Carmona-Iragui M, Videla L, Fernández S, Benejam B, Pegueroles J, Barroeta I, Altuna M, Valldeneu S, Xiao MF, Xu D, Núñez-Llaves R, Querol-Vilaseca M, Sirisi S, Bejanin A, Iulita MF, Clarimón J, Blesa R, Worley P, Alcolea D, Fortea J, Belbin O. Lleó A, et al. Among authors: sirisi s. Alzheimers Res Ther. 2021 Jun 28;13(1):119. doi: 10.1186/s13195-021-00861-0. Alzheimers Res Ther. 2021. PMID: 34183050 Free PMC article.
Enrichment of Astrocyte-Derived Extracellular Vesicles from Human Plasma.
Valle-Tamayo N, Pérez-González R, Chiva-Blanch G, Belbin O, Serrano-Requena S, Sirisi S, Cervantes González A, Giró O, Sánchez-Aced É, Dols-Icardo O, Alcolea D, Carmona-Iragui M, Jimenez A, Lleó A, Fortea J, Iulita MF. Valle-Tamayo N, et al. Among authors: sirisi s. J Vis Exp. 2022 Aug 3;(186). doi: 10.3791/64107. J Vis Exp. 2022. PMID: 35993755
Pathophysiological Underpinnings of Extra-Motor Neurodegeneration in Amyotrophic Lateral Sclerosis: New Insights From Biomarker Studies.
Reyes-Leiva D, Dols-Icardo O, Sirisi S, Cortés-Vicente E, Turon-Sans J, de Luna N, Blesa R, Belbin O, Montal V, Alcolea D, Fortea J, Lleó A, Rojas-García R, Illán-Gala I. Reyes-Leiva D, et al. Among authors: sirisi s. Front Neurol. 2022 Jan 18;12:750543. doi: 10.3389/fneur.2021.750543. eCollection 2021. Front Neurol. 2022. PMID: 35115992 Free PMC article. Review.
The Sant Pau Initiative on Neurodegeneration (SPIN) cohort: A data set for biomarker discovery and validation in neurodegenerative disorders.
Alcolea D, Clarimón J, Carmona-Iragui M, Illán-Gala I, Morenas-Rodríguez E, Barroeta I, Ribosa-Nogué R, Sala I, Sánchez-Saudinós MB, Videla L, Subirana A, Benejam B, Valldeneu S, Fernández S, Estellés T, Altuna M, Santos-Santos M, García-Losada L, Bejanin A, Pegueroles J, Montal V, Vilaplana E, Belbin O, Dols-Icardo O, Sirisi S, Querol-Vilaseca M, Cervera-Carles L, Muñoz L, Núñez R, Torres S, Camacho MV, Carrió I, Giménez S, Delaby C, Rojas-Garcia R, Turon-Sans J, Pagonabarraga J, Jiménez A, Blesa R, Fortea J, Lleó A. Alcolea D, et al. Among authors: sirisi s. Alzheimers Dement (N Y). 2019 Oct 14;5:597-609. doi: 10.1016/j.trci.2019.09.005. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31650016 Free PMC article.
26 results