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Page 1
C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection.
Desai JV, Kumar D, Freiwald T, Chauss D, Johnson MD, Abers MS, Steinbrink JM, Perfect JR, Alexander B, Matzaraki V, Snarr BD, Zarakas MA, Oikonomou V, Silva LM, Shivarathri R, Beltran E, Demontel LN, Wang L, Lim JK, Launder D, Conti HR, Swamydas M, McClain MT, Moutsopoulos NM, Kazemian M, Netea MG, Kumar V, Köhl J, Kemper C, Afzali B, Lionakis MS. Desai JV, et al. Among authors: freiwald t. Cell. 2023 Jun 22;186(13):2802-2822.e22. doi: 10.1016/j.cell.2023.04.031. Epub 2023 May 22. Cell. 2023. PMID: 37220746
Systematic single-cell pathway analysis to characterize early T cell activation.
Bibby JA, Agarwal D, Freiwald T, Kunz N, Merle NS, West EE, Singh P, Larochelle A, Chinian F, Mukherjee S, Afzali B, Kemper C, Zhang NR. Bibby JA, et al. Among authors: freiwald t. Cell Rep. 2022 Nov 22;41(8):111697. doi: 10.1016/j.celrep.2022.111697. Cell Rep. 2022. PMID: 36417885 Free PMC article.
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM, Pryor M, Yang ZH, Remaley AT, Mollnes TE, Hewitt SM, Yan B, Kazemian M, Kiss MG, Binder CJ, Halvorsen B, Espevik T, Kemper C. Niyonzima N, et al. Among authors: freiwald t. Sci Immunol. 2021 Dec 24;6(66):eabf2489. doi: 10.1126/sciimmunol.abf2489. Epub 2021 Dec 24. Sci Immunol. 2021. PMID: 34932384 Free PMC article.
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Chauss D, et al. Among authors: freiwald t. Nat Immunol. 2022 Jan;23(1):62-74. doi: 10.1038/s41590-021-01080-3. Epub 2021 Nov 11. Nat Immunol. 2022. PMID: 34764490 Free PMC article.
Response to Comments on "Aberrant type 1 immunity drives susceptibility to mucosal fungal infections".
Break TJ, Oikonomou V, Dutzan N, Desai JV, Swidergall M, Freiwald T, Chauss D, Harrison OJ, Alejo J, Williams DW, Pittaluga S, Lee CR, Bouladoux N, Swamydas M, Hoffman KW, Greenwell-Wild T, Bruno VM, Rosen LB, Lwin W, Renteria A, Pontejo SM, Shannon JP, Myles IA, Olbrich P, Ferré EMN, Schmitt M, Martin D; Genomics and Computational Biology Core16; Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD, Murphy PM, Anderson MS, Lim JK, Holland SM, Filler SG, Afzali B, Belkaid Y, Moutsopoulos NM, Lionakis MS. Break TJ, et al. Among authors: freiwald t. Science. 2021 Sep 17;373(6561):eabi8835. doi: 10.1126/science.abi8835. Epub 2021 Sep 16. Science. 2021. PMID: 34529475 Free PMC article.
SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.
Yan B, Freiwald T, Chauss D, Wang L, West E, Mirabelli C, Zhang CJ, Nichols EM, Malik N, Gregory R, Bantscheff M, Ghidelli-Disse S, Kolev M, Frum T, Spence JR, Sexton JZ, Alysandratos KD, Kotton DN, Pittaluga S, Bibby J, Niyonzima N, Olson MR, Kordasti S, Portilla D, Wobus CE, Laurence A, Lionakis MS, Kemper C, Afzali B, Kazemian M. Yan B, et al. Among authors: freiwald t. Sci Immunol. 2021 Apr 7;6(58):eabg0833. doi: 10.1126/sciimmunol.abg0833. Sci Immunol. 2021. PMID: 33827897 Free PMC article.
The effect of spironolactone on diastolic function in haemodialysis patients.
Hauser T, Dornberger V, Malzahn U, Grebe SJ, Liu D, Störk S, Nauck M, Friedrich N, Dörr M, Wanner C, Krane V, Hammer F; MiREnDa Study Group; Collaborating investigators (sites). Hauser T, et al. Int J Cardiovasc Imaging. 2021 Jun;37(6):1927-1936. doi: 10.1007/s10554-021-02176-5. Epub 2021 Feb 5. Int J Cardiovasc Imaging. 2021. PMID: 33544240 Free PMC article. Clinical Trial.
Aberrant type 1 immunity drives susceptibility to mucosal fungal infections.
Break TJ, Oikonomou V, Dutzan N, Desai JV, Swidergall M, Freiwald T, Chauss D, Harrison OJ, Alejo J, Williams DW, Pittaluga S, Lee CR, Bouladoux N, Swamydas M, Hoffman KW, Greenwell-Wild T, Bruno VM, Rosen LB, Lwin W, Renteria A, Pontejo SM, Shannon JP, Myles IA, Olbrich P, Ferré EMN, Schmitt M, Martin D; Genomics and Computational Biology Core; Barber DL, Solis NV, Notarangelo LD, Serreze DV, Matsumoto M, Hickman HD, Murphy PM, Anderson MS, Lim JK, Holland SM, Filler SG, Afzali B, Belkaid Y, Moutsopoulos NM, Lionakis MS. Break TJ, et al. Among authors: freiwald t. Science. 2021 Jan 15;371(6526):eaay5731. doi: 10.1126/science.aay5731. Science. 2021. PMID: 33446526 Free PMC article.
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