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Page 1
Tumour extracellular vesicles and particles induce liver metabolic dysfunction.
Wang G, Li J, Bojmar L, Chen H, Li Z, Tobias GC, Hu M, Homan EA, Lucotti S, Zhao F, Posada V, Oxley PR, Cioffi M, Kim HS, Wang H, Lauritzen P, Boudreau N, Shi Z, Burd CE, Zippin JH, Lo JC, Pitt GS, Hernandez J, Zambirinis CP, Hollingsworth MA, Grandgenett PM, Jain M, Batra SK, DiMaio DJ, Grem JL, Klute KA, Trippett TM, Egeblad M, Paul D, Bromberg J, Kelsen D, Rajasekhar VK, Healey JH, Matei IR, Jarnagin WR, Schwartz RE, Zhang H, Lyden D. Wang G, et al. Among authors: lyden d. Nature. 2023 Jun;618(7964):374-382. doi: 10.1038/s41586-023-06114-4. Epub 2023 May 24. Nature. 2023. PMID: 37225988 Free PMC article.
CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors.
Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, D'Angelica M, Kemeny N, Lyden D, Rafii S. Shmelkov SV, et al. Among authors: lyden d, d angelica m. J Clin Invest. 2008 Jun;118(6):2111-20. doi: 10.1172/JCI34401. J Clin Invest. 2008. PMID: 18497886 Free PMC article.
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche.
Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. Kaplan RN, et al. Among authors: lyden d. Nature. 2005 Dec 8;438(7069):820-7. doi: 10.1038/nature04186. Nature. 2005. PMID: 16341007 Free PMC article.
A TeNaCious foundation for the metastatic niche.
Matei I, Ghajar CM, Lyden D. Matei I, et al. Among authors: lyden d. Cancer Cell. 2011 Aug 16;20(2):139-41. doi: 10.1016/j.ccr.2011.08.004. Cancer Cell. 2011. PMID: 21840480 Free article.
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. Peinado H, et al. Among authors: lyden d. Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753. Nat Med. 2012. PMID: 22635005 Free PMC article.
The perivascular niche regulates breast tumour dormancy.
Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, Almeida D, Koller A, Hajjar KA, Stainier DY, Chen EI, Lyden D, Bissell MJ. Ghajar CM, et al. Among authors: lyden d. Nat Cell Biol. 2013 Jul;15(7):807-17. doi: 10.1038/ncb2767. Epub 2013 Jun 2. Nat Cell Biol. 2013. PMID: 23728425 Free PMC article.
147 results