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Fragment-based drug discovery using cryo-EM.
Saur M, Hartshorn MJ, Dong J, Reeks J, Bunkoczi G, Jhoti H, Williams PA. Saur M, et al. Among authors: hartshorn mj. Drug Discov Today. 2020 Mar;25(3):485-490. doi: 10.1016/j.drudis.2019.12.006. Epub 2019 Dec 23. Drug Discov Today. 2020. PMID: 31877353 Free article. Review.
Covert medication.
Hartshorn M. Hartshorn M. J Am Acad Psychiatry Law. 2013;41(1):154. J Am Acad Psychiatry Law. 2013. PMID: 23503186 No abstract available.
Protein-ligand docking against non-native protein conformers.
Verdonk ML, Mortenson PN, Hall RJ, Hartshorn MJ, Murray CW. Verdonk ML, et al. Among authors: hartshorn mj. J Chem Inf Model. 2008 Nov;48(11):2214-25. doi: 10.1021/ci8002254. J Chem Inf Model. 2008. PMID: 18954138
Application of fragment screening by X-ray crystallography to beta-secretase.
Murray CW, Callaghan O, Chessari G, Cleasby A, Congreve M, Frederickson M, Hartshorn MJ, McMenamin R, Patel S, Wallis N. Murray CW, et al. Among authors: hartshorn mj. J Med Chem. 2007 Mar 22;50(6):1116-23. doi: 10.1021/jm0611962. Epub 2007 Feb 22. J Med Chem. 2007. PMID: 17315856
46 results