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Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors.
Br J Cancer. 2023 Aug;129(2):309-317. doi: 10.1038/s41416-023-02276-0. Epub 2023 May 26.
Br J Cancer. 2023.
PMID: 37237172
Free PMC article.
Clinical Trial.
Niraparib and dostarlimab for the treatment of recurrent platinum-resistant ovarian cancer: results of a Phase II study (MOONSTONE/GOG-3032).
Randall LM, O'Malley DM, Monk BJ, Coleman RL, Gaillard S, Adams S, Duska LR, Dalton H, Holloway RW, Huang M, Chon HS, Cloven NG, ElNaggar AC, O'Cearbhaill RE, Waggoner S, Tarkar A, Striha A, Nelsen LM, Baines A, Samnotra V, Konstantinopoulos PA.
Randall LM, et al. Among authors: tarkar a.
Gynecol Oncol. 2023 Nov;178:161-169. doi: 10.1016/j.ygyno.2023.10.005. Epub 2023 Oct 25.
Gynecol Oncol. 2023.
PMID: 37890345
Clinical Trial.
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Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes.
Béliveau F, Tarkar A, Dion SP, Désilets A, Ghinet MG, Boudreault PL, St-Georges C, Marsault É, Paone D, Collins J, Macphee CH, Campobasso N, Groy A, Cottom J, Ouellette M, Pope AJ, Leduc R.
Béliveau F, et al. Among authors: tarkar a.
Cell Chem Biol. 2019 Nov 21;26(11):1559-1572.e9. doi: 10.1016/j.chembiol.2019.09.004. Epub 2019 Sep 19.
Cell Chem Biol. 2019.
PMID: 31543462
Free article.
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Deficits in learning and memory in mice with a mutation of the candidate dyslexia susceptibility gene Dyx1c1.
Rendall AR, Tarkar A, Contreras-Mora HM, LoTurco JJ, Fitch RH.
Rendall AR, et al. Among authors: tarkar a.
Brain Lang. 2017 Sep;172:30-38. doi: 10.1016/j.bandl.2015.04.008. Epub 2015 May 16.
Brain Lang. 2017.
PMID: 25989970
Free PMC article.
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DYX1C1 is required for axonemal dynein assembly and ciliary motility.
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K; UK10K; Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H.
Tarkar A, et al.
Nat Genet. 2013 Sep;45(9):995-1003. doi: 10.1038/ng.2707. Epub 2013 Jul 21.
Nat Genet. 2013.
PMID: 23872636
Free PMC article.
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DYX1C1 placed in a molecular context.
LoTurco JJ, Tarkar A.
LoTurco JJ, et al. Among authors: tarkar a.
Biol Psychiatry. 2013 Mar 15;73(6):497-8. doi: 10.1016/j.biopsych.2013.01.025.
Biol Psychiatry. 2013.
PMID: 23438632
No abstract available.
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