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Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis.
Kostel Bal S, Giuliani S, Block J, Repiscak P, Hafemeister C, Shahin T, Kasap N, Ransmayr B, Miao Y, van de Wetering C, Frohne A, Jimenez Heredia R, Schuster M, Zoghi S, Hertlein V, Thian M, Bykov A, Babayeva R, Bilgic Eltan S, Karakoc-Aydiner E, Shaw LE, Chowdhury I, Varjosalo M, Argüello RJ, Farlik M, Ozen A, Serfling E, Dupré L, Bock C, Halbritter F, Hannich JT, Castanon I, Kraakman MJ, Baris S, Boztug K. Kostel Bal S, et al. Among authors: kraakman mj. Blood. 2023 Aug 31;142(9):827-845. doi: 10.1182/blood.2022018303. Blood. 2023. PMID: 37249233
Rapamycin Controls Lymphoproliferation and Reverses T-Cell Responses in a Patient with a Novel STIM1 Loss-of-Function Deletion.
Karakus IS, Catak MC, Frohne A, Bayram Catak F, Yorgun Altunbas M, Babayeva R, Bal SK, Eltan SB, Yalcin Gungoren E, Esen F, Zemheri IE, Karakoc-Aydiner E, Ozen A, Caki-Kilic S, Kraakman MJ, Boztug K, Baris S. Karakus IS, et al. Among authors: kraakman mj. J Clin Immunol. 2024 Apr 5;44(4):94. doi: 10.1007/s10875-024-01682-0. J Clin Immunol. 2024. PMID: 38578569 Free PMC article.
Administration of an LXR agonist promotes atherosclerotic lesion remodelling in murine inflammatory arthritis.
Dragoljevic D, Lee MKS, Pernes G, Morgan PK, Louis C, Shihata W, Huynh K, Kochetkova AA, Bell PW, Mellett NA, Meikle PJ, Lancaster GI, Kraakman MJ, Nagareddy PR, Hanaoka BY, Wicks IP, Murphy AJ. Dragoljevic D, et al. Among authors: kraakman mj. Clin Transl Immunology. 2023 Apr 18;12(4):e1446. doi: 10.1002/cti2.1446. eCollection 2023. Clin Transl Immunology. 2023. PMID: 37091327 Free PMC article.
Hepatic FoxOs link insulin signaling with plasma lipoprotein metabolism through an apolipoprotein M/sphingosine-1-phosphate pathway.
Izquierdo MC, Shanmugarajah N, Lee SX, Kraakman MJ, Westerterp M, Kitamoto T, Harris M, Cook JR, Gusarova GA, Zhong K, Marbuary E, O-Sullivan I, Rasmus N, Camastra S, Unterman TG, Ferrannini E, Hurwitz BE, Haeusler RA. Izquierdo MC, et al. Among authors: kraakman mj. J Clin Invest. 2022 Apr 1;132(7):e146219. doi: 10.1172/JCI146219. J Clin Invest. 2022. PMID: 35104242 Free PMC article.
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L. Aaron N, et al. Among authors: kraakman mj. Elife. 2021 Jun 22;10:e69209. doi: 10.7554/eLife.69209. Elife. 2021. PMID: 34155972 Free PMC article.
RhoG deficiency abrogates cytotoxicity of human lymphocytes and causes hemophagocytic lymphohistiocytosis.
Kalinichenko A, Perinetti Casoni G, Dupré L, Trotta L, Huemer J, Galgano D, German Y, Haladik B, Pazmandi J, Thian M, Yüce Petronczki Ö, Chiang SC, Taskinen M, Hekkala A, Kauppila S, Lindgren O, Tapiainen T, Kraakman MJ, Vettenranta K, Lomakin AJ, Saarela J, Seppänen MRJ, Bryceson YT, Boztug K. Kalinichenko A, et al. Among authors: kraakman mj. Blood. 2021 Apr 15;137(15):2033-2045. doi: 10.1182/blood.2020008738. Blood. 2021. PMID: 33513601 Free PMC article.
Apoptotic Ablation of Platelets Reduces Atherosclerosis in Mice With Diabetes.
Lee MKS, Kraakman MJ, Dragoljevic D, Hanssen NMJ, Flynn MC, Al-Sharea A, Sreejit G, Bertuzzo-Veiga C, Cooney OD, Baig F, Morriss E, Cooper ME, Josefsson EC, Kile BT, Nagareddy PR, Murphy AJ. Lee MKS, et al. Among authors: kraakman mj. Arterioscler Thromb Vasc Biol. 2021 Mar;41(3):1167-1178. doi: 10.1161/ATVBAHA.120.315369. Epub 2021 Jan 14. Arterioscler Thromb Vasc Biol. 2021. PMID: 33441028 Free PMC article.
Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis.
Dragoljevic D, Lee MKS, Louis C, Shihata W, Kraakman MJ, Hansen J, Masters SL, Hanaoka BY, Nagareddy PR, Lancaster GI, Wicks IP, Murphy AJ. Dragoljevic D, et al. Among authors: kraakman mj. Clin Transl Immunology. 2020 Nov 9;9(11):e1206. doi: 10.1002/cti2.1206. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33204425 Free PMC article.
37 results