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290 results

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COURAGE-ALS: a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success.
Shefner JM, Al-Chalabi A, Andrews JA, Chio A, De Carvalho M, Cockroft BM, Corcia P, Couratier P, Cudkowicz ME, Genge A, Hardiman O, Heiman-Patterson T, Henderson RD, Ingre C, Jackson CE, Johnston W, Lechtzin N, Ludolph A, Maragakis NJ, Miller TM, Mora Pardina JS, Petri S, Simmons Z, Van Den Berg LH, Zinman L, Kupfer S, Malik FI, Meng L, Simkins TJ, Wei J, Wolff AA, Rudnicki SA. Shefner JM, et al. Among authors: henderson rd. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Aug;24(5-6):523-534. doi: 10.1080/21678421.2023.2216223. Epub 2023 May 30. Amyotroph Lateral Scler Frontotemporal Degener. 2023. PMID: 37254449 Clinical Trial.
Anthropometric measures are not accurate predictors of fat mass in ALS.
Ioannides ZA, Steyn FJ, Henderson RD, Mccombe PA, Ngo ST. Ioannides ZA, et al. Among authors: henderson rd. Amyotroph Lateral Scler Frontotemporal Degener. 2017 Nov;18(7-8):486-491. doi: 10.1080/21678421.2017.1317811. Epub 2017 Apr 27. Amyotroph Lateral Scler Frontotemporal Degener. 2017. PMID: 28446030
Hypermetabolism in ALS is associated with greater functional decline and shorter survival.
Steyn FJ, Ioannides ZA, van Eijk RPA, Heggie S, Thorpe KA, Ceslis A, Heshmat S, Henders AK, Wray NR, van den Berg LH, Henderson RD, McCombe PA, Ngo ST. Steyn FJ, et al. Among authors: henderson rd. J Neurol Neurosurg Psychiatry. 2018 Oct;89(10):1016-1023. doi: 10.1136/jnnp-2017-317887. Epub 2018 Apr 29. J Neurol Neurosurg Psychiatry. 2018. PMID: 29706605 Free PMC article.
A proposal for new diagnostic criteria for ALS.
Shefner JM, Al-Chalabi A, Baker MR, Cui LY, de Carvalho M, Eisen A, Grosskreutz J, Hardiman O, Henderson R, Matamala JM, Mitsumoto H, Paulus W, Simon N, Swash M, Talbot K, Turner MR, Ugawa Y, van den Berg LH, Verdugo R, Vucic S, Kaji R, Burke D, Kiernan MC. Shefner JM, et al. Clin Neurophysiol. 2020 Aug;131(8):1975-1978. doi: 10.1016/j.clinph.2020.04.005. Epub 2020 Apr 19. Clin Neurophysiol. 2020. PMID: 32387049 Free article. No abstract available.
Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls.
Mohanty L, Henderson RD, McCombe PA, Lee A. Mohanty L, et al. Among authors: henderson rd. Amyotroph Lateral Scler Frontotemporal Degener. 2020 Nov;21(7-8):631-634. doi: 10.1080/21678421.2020.1779303. Epub 2020 Jun 19. Amyotroph Lateral Scler Frontotemporal Degener. 2020. PMID: 32558599
A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS.
Shefner JM, Andrews JA, Genge A, Jackson C, Lechtzin N, Miller TM, Cockroft BM, Meng L, Wei J, Wolff AA, Malik FI, Bodkin C, Brooks BR, Caress J, Dionne A, Fee D, Goutman SA, Goyal NA, Hardiman O, Hayat G, Heiman-Patterson T, Heitzman D, Henderson RD, Johnston W, Karam C, Kiernan MC, Kolb SJ, Korngut L, Ladha S, Matte G, Mora JS, Needham M, Oskarsson B, Pattee GL, Pioro EP, Pulley M, Quan D, Rezania K, Schellenberg KL, Schultz D, Shoesmith C, Simmons Z, Statland J, Sultan S, Swenson A, Berg LHVD, Vu T, Vucic S, Weiss M, Whyte-Rayson A, Wymer J, Zinman L, Rudnicki SA. Shefner JM, et al. Among authors: henderson rd. Amyotroph Lateral Scler Frontotemporal Degener. 2021 May;22(3-4):287-299. doi: 10.1080/21678421.2020.1822410. Epub 2020 Sep 24. Amyotroph Lateral Scler Frontotemporal Degener. 2021. PMID: 32969758 Free PMC article. Clinical Trial.
290 results